In this study, we clearly demonstrate that formate dehydrogenase 1 (MeFDH1), a heterodimeric protein composed of alpha and beta subunits, is the essential enzyme in formate synthesis from CO2inM. extorquensAM1 cells. The MeFDH1 coding gene-knockout verified the role of this enzyme in the syn...
flexneri formate dehydrogenase gene fdnG increases host cell formate accumulation and S. flexneri plaque size. Furthermore, exogenous formate increases plaque size of the wild-type (WT) S. flexneri strain and promotes S. flexneri cell-to-cell spread. We also demonstrate that formate increases the...
16q21 21.92 CETP Cholesteryl ester transfer protein, plasma 118470 Hyperalphalipoproteinemia 16q22 28.10 NAE1 NEDD8-activating enzyme E1 subunit 1 603385 16q22.1 17.23 NQO1 NAD(P)H dehydrogenase, quinone 1 125860 Tardive dyskinesia, cancer 17p11.2 25.66 SREBF1 Sterol regulatory ele...
5013Accesses 78Citations 8Altmetric Metrics Abstract Hydrogen produced during water-rock serpentinization reactions can drive the synthesis of organic compounds both biotically and abiotically. We investigated abiotic carbon production and microbial metabolic pathways at the high energy but low diversity serp...
catalysts Article Mechanistic and Structural Insight to an Evolved Benzoylformate Decarboxylase with Enhanced Pyruvate Decarboxylase Activity Forest H. Andrews 1, Cindy Wechsler 2, Megan P. Rogers 1, Danilo Meyer 2, Kai Tittmann 2 and Michael J. McLeish 1,* 1 Department of Chemistry and Chemical...