PCR duplicates are defined as sequencing reads resulting from two or more PCR amplicons of the same DNA molecule. Although bioinformatic tools are available to identify and remove PCR duplicates during data analysis [18], minimizing ...
Another potential limitation is that amber codon suppression might impact the translation of other proteins from genes that naturally use the amber codon as a stop codon. To what extent this happens in mammalian cells is unknown. However, as most of C-terminally extended proteins get eliminated ...
Furthermore, some other groups already explored the possibility of using EV biofluids, such as cerebrospinal fluid (CSF), saliva, and plasma, as the source for PD diagnosis. CSF exosomes from patients with PD and dementia with Lewy bodies contain a pathogenic species of α-synuclein, which coul...
In addition, the genes participating glucomannan synthase actions are generally linked to the biosynthesis of medicinal polysaccharides (Zhang et al. 2016b). Mycoheterotrophic metabolomics Orchidaceae contain typical mycorrhizal plants. Their seeds possess no endosperm therefore they are devoided of nutrient...
In so far as comparisons with broadly comparable methods are possible, it appears that our approach performs rather well; that, at least, is what our brief comparison with the performance of gene/protein interaction extraction methods suggests, with both precision and recall at comparable levels. ...
The omnigenic/polygenic theory, which states that complex traits are not shaped by single/few genes, but by situation-specific large networks, offers an explanation for a major enigma in microbiology: deletion of specific small RNAs (sRNAs) playing key roles in various aspects of bacterial physiolo...
Single-molecule sequencing and conformational capture enable de novo mammalian reference genomes. bioRxiv. 2016;1:064352. Ashrafi H. Using spinach to compare technologies for whole genome assemblies. In: Plant and Animal Genome Conference XXIII 2015. San Diego, CA; 2015. Bertioli DJ, Cannon SB,...
What is a genetic mutation: A. Remove the intron from the gene-coding exon. B. change a DNA molecule C. are relatively common D. both A and C Which of the following causes a change in a single nucleotide in the DNA...
Tissues are complex mixtures of different cell subtypes, and this diversity is increasingly characterized using high-throughput single cell analysis methods. However, these efforts are hindered, as tissues must first be dissociated into single cell suspe
(Fig.4e). The electron micrographs mirror what was observed with fluorescence microscopy; Fionnbharth begins forming tightly organized phage assembly domains 2–3 h after infection andlsr2deletion results in reduced mature phage capsid formation.∆lsr2infected cells contain fewer electron-dense ...