PCR duplicates are defined as sequencing reads resulting from two or more PCR amplicons of the same DNA molecule. Although bioinformatic tools are available to identify and remove PCR duplicates during data analysis [18], minimizing P...
Gordonia,StreptomycesandMicrobacterium54,55(Fig.6a), raising the possibility that phages encode these to counter host defence mechanisms involving loss of Lsr2 activity. These phage-encodedlsr2-like genes span substantial sequence diversity and many are distantly related to host...
Cellular plasticity describes the ability of cells to transition from one set of phenotypes to another. In melanoma, transient fluctuations in the molecular state of tumor cells mark the formation of rare cells primed to survive BRAF inhibition and repro
Structure-based protein and small molecule generation using EGNN and diffusion models: A comprehensive review Farzan Soleymani, Eric Paquet, Herna Lydia Viktor, Wojtek Michalowski Computational and Structural Biotechnology Journal (2024) Machine learning in biological physics: From biomolecular prediction to ...
In addition, the genes participating glucomannan synthase actions are generally linked to the biosynthesis of medicinal polysaccharides (Zhang et al. 2016b). Mycoheterotrophic metabolomics Orchidaceae contain typical mycorrhizal plants. Their seeds possess no endosperm therefore they are devoided of nutrient...
This has always been a bit difficult to prove, though, because the closer the donor and recipient the harder it will be to detect transfers, just from the sequences of their genes. So what Andam and Gogarten do here, in an extension of their recent PNAS paper, is address an interesting...
Aptamers are DNA or RNA oligonucleotides that bind to a specific target molecule (pathogen) with high affinity and specificity very similar to the interaction between antigen and antibody (Li et al., 2019; Yeong et al., 2017). Aptamer-based immunosensors emerged as alternatives to antibody-based...
1743 „Genes, Environment and Inflammation”. Funding This work was founded by the Norwegian PSC Research Center (NoPSC) and the DFG Cluster of Excellence No. 306 “Inflammation at Interfaces”. Availability of data and materials The datasets analysed during the current study are available in ...
What are the chemical components of a DNA molecule? What do DNA repair genes do? What are DNA repair genes? What are the levels of DNA structure? What is DNA ligase used for? What does a DNA-binding protein do? What does the information in DNA tell a cell how to make?
In so far as comparisons with broadly comparable methods are possible, it appears that our approach performs rather well; that, at least, is what our brief comparison with the performance of gene/protein interaction extraction methods suggests, with both precision and recall at comparable levels. ...