Chronic diseases (e.g., diabetes and diabetic neuropathy) Infections (e.g., athlete's foot, toenail fungus [onychomycosis]) The Most Common Causes of Foot Pain Diagnosis To diagnose problems with the parts of the foot, a healthcare provider or a foot specialist (orthopedist) will look at y...
Journal of Foot and Ankle Research BioMed Central Research Open Access Threshold for detection of diabetic peripheral sensory neuropathy using a range of research grade monofilaments in persons with Type 2 diabetes mellitus Mary P Thomson*1, Julia Potter2, Paul M Finch3 and Richard B Paisey4 ...
(DFUs) generally reflects trauma superimposed upon peripheral neuropathy and peripheral arterial disease. In the UK, approximately 2–2.5% of the diabetic population have a foot ulcer at any one time, representing a significant health burden and costing the NHS approximately £1 billion annually (...
This is vitally important in the diagnosis of Peripheral Arterial Disease ("PAD"), because at least two-thirds of PAD patients are asymptomatic. A large proportion have lost the ability to feel pain due to diabetic neuropathy which renders the foot numb. ...
In persons with diabetes-related foot complications, signs and symptoms of inflammation may, however, be masked by the presence of peripheral neuropathy, peripheral artery disease (PAD), or immune dysfunction. A patient with diabetes-related complications ...
NeuroQoL was designed to assess HRQOL in patients with diabetes complicated by peripheral neuropathy and DFUs. It has been validated against the SF-12 to show construct validity and sensitivity to neuropathic symptoms, which the SF-12 (as a generic instrument) is unable to detect. Factor analys...
In diabetic foot disease, adverse cardiovascular outcomes outweigh adverse limb outcomes, and 5-year mortality rates are higher than those with the common cancers. The main causes of this high associated mortality are cardiac or cerebrovascular events. C
(e.g. diabetic peripheral neuropathy), surgery (e.g. joint fusion), or trauma (e.g. major fractures) that had affected lower limb sensation or their ability to walk/run and if relevant to the imaging modality of interest. The same exclusion criteria were applied to the control group ...
NeuroQoL has proven proficient in assessing the impact of advancing neuropathy on HRQOL. It is less useful in showing the relationship between DFU severity and HRQOL. This may reflect the tool's focus on neuropathic (as opposed to ulcerative) symptoms. It could also be a consequence of ...
SpO2 was reduced in people with diabetes, and especially in those with neuropathy. Yudovsky et al. [6] also used HSI in the visible spectrum (450–700 nm) to predict tissue breakdown. A two-layer (epidermis, dermis) skin model was used to fit to the measured data and obtain an index...