Introduction Atypical follicular adenoma (AFA) is a rare variant of follicular adenoma (FA) of thyroid. It is characterized by thick capsule, increased cellularity, hypercellularity along the tumor-capsule interface, increased mitotic activity including atypical forms, necrosis, prominent nucleoli and ...
psammoma,sand tumor- a tumor derived from fibrous tissue of the meninges or choroid plexus or certain other structures associated with the brain; characterized by sandlike particles teratoma- a tumor consisting of a mixture of tissues not normally found at that site ...
There is loss of heterozygosity at 20 percent per chromosome arm, in comparison to this only being 6 percent in follicular adenoma and 2.5 percent in papillary carcinoma. TERT promoter mutations occur in about 20 percent of cases of follicular carcinomas, which are linked to more tumor ...
Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid gland and has a greater propensity for haematogenous metastasis. However, the preoperative differentiation of FTC from follicular thyroid adenoma (FTA) is not well establi
The macrofollicular subtype had predominantly sheets or spherules with abundant, thick background colloid. Nuclear pseudoinclusions and psammoma bodies were absent and multinucleated giant cells rarely found. Pitfalls leading to a "false-positive" FVPCT diagnosis included oncocytic adenoma (in 2 cases)...
clustered with BRAF V600E-type tumors, without overlapping with the RAS or PAX8/PPARγ cluster of tumors.6 Both RAS (H, N, or KRAS) or PAX8/PPARγ is seen in thyroid follicular-patterned tumors: follicular adenoma, fol- licular carcinoma, and follicular variant of papillary thyroid ...
Signet-ring follicular adenoma of the thyroid diagnosed by fine needle aspiration. Report of a case with cytologic description. BACKGROUND: Follicular cells of the thyroid may undergo squamous, oncocytic or clear cell metaplastic changes. Of these, the clear cell change with signet-... D Elsahr...
The intronicPLCB1InDel is the first variant found in familial multiple papilloid adenomata-type MNG patients with more likelihood of progression to PTC and also found in a subset of patients with sporadic MNG [59,60]. The InDel may contribute to MNG development through overexpression of phospho...
Follicular carcinoma is divided into minimally invasive and widely invasive types and also includes lesions with oncocytic (Hürthle cell) morphology. Minimally invasive follicular carcinoma is indistinguishable grossly from follicular adenoma, except for a thick capsule that separates it from the surrounding...
Follicular Adenoma, Oncocytic Variantdoi:10.1007/978-3-642-16483-5_2236Hurthle Cell Adenoma and CarcinomaSpringer Berlin HeidelbergSpringer Berlin Heidelberg