Folic acid deficiency plays a central role in the aetiology of many congenital anomalies including neural tube defects. Protective effect of folic acid on embryo may be acquired only if taken periconceptionally.The aim of the study was to investigate the awareness about folic acid among women of...
Folic acid, water-soluble vitamin of the B complex that is essential in animals and plants for the synthesis of nucleic acids. Folic acid was isolated from liver cells in 1943. The vitamin has a wide variety of sources in the human diet, including leafy
The results of a randomized double-blind prevention trial conducted at 33 centers in seven countries to determine the effects of folic acid supplements around the time of conception in the prevention of neural tube defects is reported by the MRC Vitamin Study Research Group, Department of ...
MLPA as first screening method for the detection of microduplications and microdeletions in patients with X-linked mental retardation: Erratumdoi:10.1097/GIM.0b013e3182326e9dJamesEHaddowNatureGenetics in Medicine Official Journal of the American College of Medical Genetics...
Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention (corrected; erratum to be pu... Hong SX, Correa A: Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube ...
3. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet 1991;338:131– 137. 4. Wald NJ, Law MR, Morris JK, Wald DS. Quantifying the effect of folic acid. Lancet 2001;358:2069 –2073. In Reply: We thank Dr...
Single-wall carbon nano-tubes were used to modify the surface of a glassy carbon electrode (GC) and applied in the determination of folic acid with voltammetry. The experiments demonstrated that the presence of a carbon nano-tube film on the electrode greatly increased the reduction peak current...
Objective: To study the effect of increased folic acid intake on the prevalence of neural tube defects (NTD) in The Netherlands. Study design: Using the capture–recapture method, the prevalence of NTD was estimated on the basis of five different registries on births affected by NTD. Results:...
Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects. JAMA 1989; 262: 2847–2852. Article CAS Google Scholar Czeizel AE, Dudas I . Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J ...
7 ⅐ No. 4 ACMG practice guideline Folic acid and neural tube defects Helga V. Toriello, PhD, for the Professional Practice and Guidelines Committee Key Words: folic acid supplementation, neural tube defects, prenatal diet, congenital anomalies Major congenital anomalies occur in 2% to 3% of ...