The effects offolatedeficiency are very similar to B12deficiency. Both cause megaloblastic changes in the marrow andmacrocytic anaemia, defectiveDNA synthesisand impaired production of blood cells and, ultimately, of many other cells. Folatedeficiency in adults leads toanaemia.Folic acid deficiencyin ...
Folic aciddeficiency should be suspected in patients with macrocytic anemia, depression, or dementia, particularly when vitamin B12deficiency has been ruled out as a cause. Electrophysiologic tests, imaging, and somatosensory evoked responses may be useful. ...
Liu Y K (1975) Folic acid deficiency in sickle cell anaemia. Scand J Haematol 14, 71-79.Liu YK. Folic acid deficiency in sickle cell anaemia. Scand J Haematol 1975;14:71-79.Liu, Y.K. ( 1975 ) Folic acid deficiency in sickle cell anaemia . Scandinavian Journal of Haematology , 14 ...
THE occurrence of folic acid deficiency anaemia, complicating the use of a wide range of anti-epileptic drugs, has led to the suggestion that these compounds produce their effect by antagonizing folic acid in the brain. This implies that folic acid can act as a cerebral excitant. However, ...
These findings are consistent with other observations that folate requirement may be increased in chronic haemolytic disorders and suggest that erythrocyte folate values should be obtained in sickle-cell patients suspected of having folate deficiency. 展开 关键词: folic acid sickle cell anaemia DOI: ...
Megacytotic anaemia due to folic acid deficiency (MCV 117 fl, folio acid in plasma 1.6 ng/ml) was found without further laboratory findings of a HELLP syndrome. Anaemia was interpreted as partial pernicious anaemia. After supplementation with folic acid and parental vitamin B12 the pregnancy was...
The plasma clearance test for folic acid deficiency and the method of estimating folic acid absorption previously described (Chanarin et al., Abst. 5916, Vol. 28; Brit. J. Haematol., 1958, 4, 435) were applied to the study of megaloblastic anaemias which require treatment with folic acid....
(Elements & Compounds) any of a group of vitamins of the B complex, including pteroylglutamic acid and its derivatives: used in the treatment of megaloblastic anaemia. Also called:folacin [C20: from Latinfoliumleaf; so called because it may be obtained from green leaves] ...
Folic-acid Studies in Megaloblastic Anaemia Due to Primidone folic acidfolic acid deficiencyintravenous injectionSevere megaloblastic anaemia developed in a patient after 2 years' treatment with the anticonvulsant primidone;... I Chanarin,PC Elmes,DL Mollin - 《British Medical Journal》 被引量: 49发表...
A deficiency can show up as white flecks in the finger nails Research suggests that supplementation duringpregnancycan prevent anaemia in women and reduces the risk of complications and birth defects. Folic acid aidsamino acid metabolism- remember that you make some of them yourself. And research ...