Accordingly, we have designed conjugates of folic acid with anticancer peptides able to bind human thymidylate synthase (hTS) and enter cancer cells through folate receptor α (FRα) highly expressed by several cancer cells. Mechanistic analyses and molecular modeling simulations have shown that these...
Folic acid, also known asfolate, is one of the B vitamins and has other industrial uses. Folic acid (also known as vitamin B9, vitamin Bc or folacin) and folate, as well as pteroyl-L-glutamic acid, pteroyl-L-glutamate, and pteroylmonoglutamic acid are forms of the water-soluble vitam...
GO-PEG-Fol consists of a nano-GO sheet, obtained by fragmentation of GO by means of non-equilibrium plasma etching, fully functionalized with folic acid-terminated PEG2000 chains through amidic coupling and azide-alkyne click cycloaddition, which we showed as active targeting agents to selectively ...
A process for the representation of 6 - amino - 9 - oxy - folic acidZAKRZEWSKI SIGMUNDTSCHESCHE RUDOLF DR.
stressed plants while in non-stressed by 38 to 120%. However, a minimum level of H2O2was noted in the case of the combined effect of folic acid and consortium by 120% in comparison with the respective control. The graphical representation of GR and H2O2is shown in Fig.7C and D ...
In this study, a folic acid (FA) -modified gene delivery system based on the self-assembly of DOTAP, MPEG-PCL-MPEG, and FA-PEG-PCL-PEG-FA, namely F-PPPD, was developed to deliver plasmids encoding the immunostimulating chemokine CKb11. The delivery of plasmid CKb11 (pCKb11) by F-...
Phase contrast images are not a complete representation of all the spheroids that were measured and plotted in the bar graph. Abbreviations: SMA, poly(styrene-alt-maleic anhydride); FA, folic acid; DABA, 2,4-diaminobutyric acid; Cur, curcumin; CA, cell aggregate. Figure 7. Changes in ...
Scheme 1. Schematic representation of the synthesis of polymers (considering the theoretical numbers of monomers and folic acid units). Figure 1. Juxtaposition of 1H NMR spectra of folic acid, folate-conjugated PTF-1, PTF-2, and PTF-3 polymers, and an example of non-conjugated polymer PT-...
The results of our study suggest that nutraceutical combination of leucoselect® phytosome®, red yeast rice, policosanol and folic acid is effective in term of LDL-C serum level reduction and shows an anti-inflammatory effect, reducing both the CPR and PLA2. The explanation of this ...