Folic acid and methotrexatePeter M Farr
Effects of folic acid and methotrexate on arginase activity in regenerating rat liver tissue. Arch Int Physiol Biochim Biophys 1993; 101(5):271-273Nikolić J, Bjelaković G, Kocić G. Effects of folic acid and methotrexate on arginase activity in regenerating rat liver tissue. Arch Int ...
and for which hyperhomocysteinaemia is now recognized as an independent risk factor.“ If one cause of the elevated homocysteine levels is methotrexate, folic acid could help prevent that.Folic
满意答案 Avoid folic acid supplements - folic acid (folate) can interfere with the action of methotrexateduring a medical abortion. 避免叶酸补充剂 -叶 酸(叶酸) ,可以干预行动甲氨蝶呤在药物流产。blog.tianya.cnConsume 400 micrograms (mcg) per day of synthetic folic acid (from fortified foods an...
Folic acid is effective in the treatment of certain forms of anemia and other diseases. It is prepared by the condensation of 2, 4, 5-triamino-6-hydroxy pirimidine, 1,1, 3-trichloroacetone, and para-aminobenzoyl glutamic acid. Aminopterin and methotrexate, which have a structure similar to...
Folic acidis nearly completely and rapidly absorbed from the proximal portion of the gastrointestinal tract. Peak serum levels occur 30–60 min after oral administration. Only trace amounts of folate are usually found in the urine, but large doses of the vitamin may exceed renal reabsorption allo...
Folic acid may also be used to control high levels of homocysteine, prevent serious birth defects in pregnant women or women who think they may be pregnant, and prevent methotrexate-induced folate deficiency in people prescribed methotrexate.
Folic acid CAS:59-30-3 MW:441.39746 MF:C19H19N7O6 Folic acid (folate) is a kind of B-vitamin which is mainly present in the liver and kidney. It has various kinds of pharmacological and physiological effects. It is involved in amino acid metabolism, purine and pyrimidine synthesis, and...
N. (2005), Folic acid and folinic acid supplements and methotrexate therapy: Comment on the article by Morgan et al. Arthritis & Rheumatism, 52: 1338–1339. doi: 10.1002/art.20972 Author Information New York University Medical Center, New York, NY Publication History Issue published online: 7...
Dosage for Folic Acid The usual therapeutic dosage of folic acid in adults and children (regard less of age) is up to 1 mg daily. What Drugs, Substances, or Supplements Interact with Folic Acid? Folic acid may interact with phenytoin and other anticonvulsants, methotrexate, barbiturates, alcoh...