FOLFOXIRI Regimen a New Upfront Option for Some Patients with Metastatic Colorectal CancerWayne Kuznar
In order to promote the standardized and rational application of FOLFOXIRI regimen by clinicians in China, "Chinese Expert Consensus on the Clinical Application of the Chinese Modified Triplet Combination with Irinotecan, Oxaliplatin, and Continuous Infusional 5⁃Fluorouracil/Leucovorin for Colorectal ...
2. Wang DS, Ren C, Li SS et al. Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomiz...
Trastuzumab deruxtecan in patients in the USA and Europe with HER2-positive advanced gastric or gastroesophageal junction cancer with disease progression on or after a trastuzumab-containing regimen (DESTINY-Gastric02): primary...
The outcome of palliative chemotherapy with the modified FOLFOXIRI regimen in the treatment of middle-aged and elderly patients with advanced gastric cancer 在线阅读 免费下载 引用 收藏 分享 摘要 目的 探讨5-氟尿嘧啶/亚叶酸钙+奥沙利铂+伊立替康(FOLFOXIRI)改良方案姑息化疗治疗中老年晚期胃癌的效果。
The FOLFOXIRI regimen, which combines 5 ? fluorouracil / leucovorin, oxaliplatin, and irinotecan, is a high ? intensity and highly effective chemotherapy regimen. However, the original regimen is poorly tolerated in Chinese patients. In order to promote the standardized and rational application of ...
ConclusionThe mFOLFOXIRI regimen with reduced dose can be safely used in advanced CRC and has achieved promising results in terms of short-term efficacy. KEYWORDS: Colorectal neoplasms;Irinotecan;Oxaliplatin;5-fluorouracil;Triplet regimen Corresponding author: Deng Yanhong, Email: moc.36152560152931 FUNDI...
The FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) regimen has been shown to be better than FOLFIRI (fluorouracil, folinate, and irinotecan) in a phase 3 trial in patients with metastatic colorectal cancer. Results of various studies have shown that the addition of bevacizumab to ...
This FOLFOXIRI regimen should be considered as neoadjuvant treatment in initially unresectable metastatic colorectal cancer patients. KeywordsMetastatic colorectal cancer–Neoadjuvant chemotherapy–FOLFOXIRI–Surgical resection of metastases 展开 关键词: Metastatic colorectal cancer Neoadjuvant chemotherapy FOLFOXIRI ...
A modified FOLFOXIRI regimen (irinotecan 150 mg/m2, oxaliplatin 85 mg/m2, leucovorin 200 mg/m2) was administered on day 1, including a fluorouracil 2,400 mg/m2 continuous infusion for 48 h started on day 1 and then repeated every 14 days. The patients were given up to 5 cycles of nCT...