Kelemen L E.The role of folate receptor alpha in cancer development, progression and treatment:cause, consequence or innocent bystander?. International Journal of Cancer . 2006Kelemen LE. The role of folate receptor α in cancer development, progression and treatment: cause, consequence...
Kelemen, L. E. The role of folate receptor alpha in cancer development, progression and treatment: cause, consequence or innocent bystander?Int. J. Cancer119, 243–250 (2006). ArticleCASGoogle Scholar Kamen, B. A., Wang, M. T., Streckfuss, A. J., Peryea, X. & Anderson, R. G. ...
Folate receptor-alphaOvarian cancerImmunohistochemistryErratum to: Cell Oncol. (2011) DOI 10.1007/s13402-011-0052-6 The affiliations of the authors of the above mentioned article, published in Cellular Oncology, volume 35, issue 1, February 2012, pp. 9鈥 18, should read: L. M. A. Crane ....
Nutt, J. E. et al. The role of folate receptor alpha (FRα) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy.Br. J. Cancer102, 553–560 (2010). ArticleCASPubMedPubMed CentralGoogle Scholar O’Shannessy, D. J., Somers, E. B., Maltzman, J., Smal...
Integrin and transferrin receptor 1, overexpressed in cancer cells, have been recently leveraged for TPD. Degraders that recruit these receptors hold the possibility of selectively depleting the extracellular proteins in cancer cells. However, the cancer selectivity has not been examined25,26. Similar ...
Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and presents a major clinical challenge due to limited treatment option
Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery 6.4Folate Receptor FR is membrane-bound protein on the cell surface, which strongly binds withfolic acidmolecules in neutral pH and transports them into cells. Folate mainly plays a role in DNA synthesis, methylation, and repair ...
However, its expression in ovarian cancer is poorly defined. Thus, while folate may be vital for the growth of both normal and tumor cells, different mechanisms may be involved. In the present study, the expression levels of FRα and RFC as well as the functional impact of folate in ...
Folate receptor alpha (FRα) is a promising biomarker and therapeutic target for ovarian, breast, brain, lung, and colorectal cancers.3,4,5,6,7,8Our previous work in large clinically relevant breast cancer cohorts demonstrated substantial FRα expression at the level of both mRNA (The Cancer ...
(2007). Human reduced folate carrier: translation of basic biology to cancer etiology and therapy. Cancer Metastasis Reviews, 26(1), 111–128. Article CAS PubMed Google Scholar Kelemen, L. E. (2006). The role of folate receptor alpha in cancer development, progression and treatment: cause...