The restless legs syndrome could represent a folate responsive disorder in both patients with acquired-folate deficiency and those with familial symptomatology. Patients with acquired folate-deficiency could be divided into two subgroups. (i) those with minor neurological signs (restless legs...
Glossitis Maternal deficiency: fetal spina bifida or anencephaly Unlike vitamin B12 deficiency, folate deficiency does not typically cause neurological symptoms; rarely, neuropsychiatric conditions (e.g., cognitive impairment, depression) or peripheral neuropathy can occur. [7][8] ©...
Cerebral folate deficiency (CFD) is defined as any neurological syndrome associated with a low cerebrospinal fluid (CSF) concentration of 5-methyltetrahydrofolate (5MTHF) in the presence of normal peripheral folate status. CFD has a wide clinical presentation, with reported signs and symptoms generall...
Folate deficiency is a common nutritional deficiency that can be caused by a lack of dietary folate intake, with specific symptoms.
Polyneuropathy and folate deficiency. 喜欢 0 阅读量: 12 作者: M,I,Botez,J,M,Peyronnard,J,Bachevalier,L,Charron 摘要: We studied five patients (two men and three women, age between 58 and 76 years) with clinical and electrophysiological signs of polyneuropathy. Routine neurological, ...
try, Sakado, Saitama, JapanOBJECTIVE: Human sepiapterin reductase(SPR) deficiency has unique characteristics that itdoes not cause hyperphenylalainemia and consi-derable amount of BH4 is generated in thepatients, and that they develop neurologicalsymptoms caused by monoamine neurotransmit-ter deficiency....
adult-onset cerebral folate deficiency:objective typical autoimmune cerebral folate deficiency is characterized by normal early development followed by abrupt neurological regression. at approximately 4 m... ZS Md - 《Jama Neurology》 被引量: 0发表: 2012年 Prevention of behavioral deficits in rats expo...
In generalized folate deficiency caused by hereditary folate malabsorption (MIM #229050)17 or severe dietary folate deficiency, hematological and neurological symptoms develop within the first months of life and may lead to death in infancy when untreated. In contrast, our patients developed symptoms ...
Using 5-MTHF instead of folic acid reduces the potential for masking haematological symptoms of vitamin B12 deficiency, reduces interactions with drugs that inhibit dihydrofolate reductase and overcomes metabolic defects caused by methylenetetrahydrofolate reductase polymorphism. Use of 5-MTHF also prevents ...
This view goes beyond the idea of a dietary requirement to prevent signs and symptoms of clinical deficiency towards one of achieving an optimal status to reduce risk of certain chronic diseases, and includes the concept that an individual's genetic make-up may substantially affect the vitamin ...