Clinically, folate deficiency causes a characteristic macrocytic anemia in peripheral cells, which may be mirrored by megaloblastic changes in the bone marrow. Biochemical characteristics of deficiency include low serum and red cell folate concentrations and raised plasma homocysteine. The definition above ...
Severe folate deficiency anemia associated with the use of a PARP inhibitor (olaparib) in a patient with fallopian tube cancer Treatment of cancer patients with olaparib (PARP inhibitor) is associated with an increased risk of anemia, which is seen in a majority of treated patients. However, sym...
Prevalence of Iron Deficiency and Iron Deficiency Anemia in High-School Girl Students of Yazd Introduction: It is generally assumed that 50% of the cases of anemia are due to iron deficiency. The most severe consequence of iron depletion is iron def... H Mozaffarikhosravi,MN Shadkam,Y Naghiae...
Deficiency Conditions and Symptoms Summary Register to view this lesson Are you a student or a teacher? Biology 105: Anatomy & Physiology 20chapters |190lessons|15flashcard sets Ch 1.Anatomy and Physiology Overview Body Structure | Definition, Function & Examples7:42 ...
What Are Flour Bugs? Are Peanuts Actually Good for You? These 2 Nutrients Could Help You Lose Weight FDA Updates Its Definition of ‘Healthy’ Food 10 Little-Known Tart Cherry Juice Benefits These Foods Pack More Potassium Than a Banana
Folate or cobalamin deficiencies are usually detected by hematologic abnormalities, such as a macrocytic megaloblastic anemia, or often milder signs, such ... J Zittoun,R Zittoun - 《Seminars in Hematology》 被引量: 229发表: 1999年 Clinical and laboratory features and sequelae of deficiency of...
[99] In this sense, the definition of a standardized clinical assessment is essential for developing new therapeutic strategies, including folate and other B vitamin supplements, and reducing morbidity and mortality in epilepsy patients under long-term therapy. Results have shown that the condition of...
Three types of morphologic abnormalities of megaloblasts in the bone marrows of eight patients with severe untreated pernicious anemia and two patients with folate deficiency are described. A fourth type of abnormality, probably indicating disturbances in hemoglobin synthesis, was also observed in megalo...
Reducedcarrier plays a role inabsorption, thereby transporting 5-methyltetrahydrofolate, the metabolically active form of folate, into a variety of cells646566,67In combination with other polymorphisms involved in this metabolism A80G has been indicated as risk allele for Downs syndrome.68,69Shaw et...
Watkins D., Rosenblatt D.S. Genetic heterogeneity among patients with methylcobalamin deficiency: definition of two complementation groups, cblE and cblG. J Clin Invest 81: 1690–1694, 1988 ArticlePubMedCASGoogle Scholar Rosenblatt D.S., Cooper B.A., Pottier A., Lue-Shing H., Matiaszuk N...