For the first time ever, researchers have delivered an antibody therapy drug directly into the brain to target breast cancer metastases. A team atSunnybrook Health Sciences Centrein Toronto used MR-guided focused ultrasound (MRgFUS) to non-invasively and temporarily open the blood–brain barrier (...
Focal therapy (FT) is emerging as a promising alternative for intermediate-risk PCa, aiming to selectively target localized cancerous lesions while preserving healthy tissue. This review explores emerging FT modalities for PCa treatment, focusing on transrectal MRI-guided focused ultrasound surgery (MR...
Reevaluation of the effectiveness of Magnetic Resonance-High Intensity Focused Ultrasound (MR-HIFU) therapy for uterine fibroids by excluding studies with restrictive treatment protocols that are no longer used. Methods The National Guideline Clearinghouse, Cochrane Library, TRIP, MEDLINE, EMBASE and WHO...
Parkinson’s disease (PD) is a progressive disorder that affects the nervous system and causes regions of the brain to deteriorate. In this study, we investigated the effects of MR-guided focused ultrasound (MRgFUS) for the delivery of human mesenchymal
The blood brain barrier (BBB) is a major obstacle to the delivery of therapeutics to the brain. Focused ultrasound (FUS) in combination with microbubbles can non-invasively open the BBB in a targeted manner. Bolus intravenous injections of microbubbles a
Klingler, H.C., Susani, M., Seip, R., Mauermann, J., Sanghvi, N., and Marberger, M.J., A novel approach to energy ablative therapy of small renal tumours: laparoscopic high-intensity focused ultrasound, Eur. Urol., 53 (2008) 810–816. Article PubMed Google Scholar Kohrmann, ...
High-intensity focused ultrasound is an example of focal therapy in which an ultrasound transducer focuses sound waves to generate heat at a single point within the body and destroy the target tissue. In the past, it has been performed under ultrasound guidance, but ultrasound does not visual...
Focused ultrasound ablation been assessed for safety and efficacy in epilepsy therapy [10], and although clinical studies specifically using FUS-BBBO for epilepsy have yet to be conducted, it is an area of developing interest [80]. Zhang et al. used Precise Intracerebral Non-invasive Guided Surg...
MAGNETIC RESONANCE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND – MATHEMATICAL MODELING OF AN INNOVATIVE, STATE OF THE ART TECHNOLOGY FOR CANCER THERAPY*Traditionally chemotherapy, radiotherapy, and surgery have been the primary therapeutic interventions used to treat cancers. Over the last decade, High ...
N.L. (chair), K.H., and S.E.B. have received an honorarium for serving on an expert steering committee on focused ultrasound in AD. K.H. is an inventor on intellectual property owned by Brigham and Women’s hospital in Boston and Sunnybrook Research Institute in Toronto related to intr...