Currents were activated by BzATP (100 μ M; Sigma-Aldrich) applied for 3 s at 2 min inter- vals onto the cell under investigation by means of a pneumatic drug ejection system (PDES-02DX, NPI Electronic GmbH, Germany). A-438079 (A43; 10 μ M; Sigma-Aldrich) was applied...
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For instance, one study reported anti-inflammatory activity in rats treated intracolonically or orally with nanocrystalline silver (NPI 32101), showing substantially reduced colonic inflammation and rapid dose-dependent healing [329]. AgNPs that were delivered topically on wound mice models, and showed...
Dendritic nanoparticles such as poly(amidoamine) (PAMAM) dendrimers have already been explored for applications such as targeted drug delivery in cancer therapy [25–28], gene delivery [29–31], medical imaging applications [32–35], and also the mannosylated form of PAMAM dendrimers has been ...