Induction and expression of GST-Pi foci in the liver of Cyclophosphamide-administered rats. Arikketh Devi and Halagowder Devaraj. Toxicology . 2006A. Devi, H. Devaraj, Induction and expression of GST-Pi foci in the liver of cyclophosphamide-administered rats, Toxicology 217 (2006) 120-128....
The distributions of gamma-glutamyltransferase (GGT) and the placental form of glutathione S-transferase (GSTP) were examined in the livers of 18-month-old and 23-month-old SPF F344/DuCrj rats of both sexes. The number of the enzyme-altered foci in males was greater than in females, and...
Epidermal Growth Factor (EGF), is a potent mitogenic polypeptide that is produced mainly in the salivary glands and the Brunner's gland of the duodenum. It has been demonstrated to be mitogenic, both in vivo and in vitro to a wide variety of epithelial cells including the liver parenchymal ...
DNA damage triggers imbalance of proliferation and apoptosis during development of preneoplastic foci in the liver of Long-Evans Cinnamon rats The mutant strain Long-Evans Cinnamon (LEC) rat accumulates copper, resulting in spontaneous hepatitis and subsequent development of hepatocellular carcino... G...
Cytochemical and electron microscopic investigations of neoplastic nodules induced in the rat liver by nitrosomorpholine or thioacetamide show that most neoplastic nodules are comprised of a rather heterogeneous cell population. At least... P Bannasch - 《Cancer Research》 被引量: 239发表: 1976年 An...
Metastatic poorly differentiated carcinomas often represent diagnostic difficulties in surgical pathology. Therefore, the expression of cytokeratins of dif... KD Shah,SS Tabibzadeh,MA Gerber - 《American Journal of Clinical Pathology》 被引量: 54发表: 1987年 Liver tumors and possible preneoplastic les...
The present study aimed to further characterize the tissue features associated with this singular nosological form of HCC in order to gain insight into the natural history of the disease. We performed an exploratory analysis of the histology of both tumor and non-tumor liver (NTL) tissues from...
Enzyme-altered foci (EAF) were induced in the liver of female by 70% partial hepatectomy (PH), followed by a single intragastric administration of () at a dose of 10 mg/kg. The stability and response of these foci to various doses of the... G Thomas,HA Campbell,HC Pitot - 《Carcino...
Four pesticides were examined for hepatopromoting activity using a medium-term bioassay based upon induction of glutathione S-transferase placental form (GST-P) positive foci in the rat liver. Male F344 rats were initially injected with diethylnitrosamine (DEN; 200 mg/kg body weight) ...
Comparison of potentiality to induce graft-versus-host reaction with small bowel, pancreas/spleen, and liver transplantation in the rat. Although small bowel transplantation (SBT), or pancreas-spleen transplantation (PST) often lead lo lethal graft-versus-host reaction (GVHR) in experimental... Kob...