Generalized onsetFocal evolutionFocal seizuresSeizure classificationSeizure typesInterictal epileptiform dischargesPurpose: We report clinical and electrographic features of generalized onset seizures with focal evolution (GOFE) and present arguments for the inclusion of this seizure type in the seizure ...
Generalized epileptic discharges leading into focal onset seizure: GOFE seizures as the initial diagnosis of epilepsy doi:10.1007/s00415-024-12841-zSpringer Berlin HeidelbergJournal of NeurologyDavide Gusmeo Curtihttps://ror.org/039zxt351grid.18887.3e0000000417581884Neurology UnitIRCCS San Raffaele ...
Purpose: The study of intracerebral EEG seizure onset patterns (SOP) is crucial to accurately define the epileptogenic zone and guide successful surgical resection. Until now, several SOP have been described using distinct recording methods (subdural, depth electrode), mostly in temporal lobe epilepsies...
Focal-onset seizures are among the most common forms of seizures in children and adolescents and can be caused by a wide diversity of acquired or genetic etiologies. Despite the increasing array of antiseizure drugs available, treatment of focal-onset seizures in this population remains problematic,...
Objective To assess the effectiveness and tolerability of perampanel (PER) monotherapy in routine clinical practice for the treatment of focal onset and generalized tonic‐clonic seizures (GTCS). Methods This multicenter, retrospective, observational study was conducted in patients aged ≥12 years treated...
topological changes and disease-related gene expression maps were evaluated against spatial permutation and “random-gene” null models37,38. Reproducibility of our findings was also assessed across sites, variable network construction approaches, and clinical variables (side of seizure onset, disease ...
Your child will also get a magnet that acts as a switch to turn the device on. If your child feels a seizure coming, they can hold it over the device to get the signals pulsing. This may stop the seizure or at least shorten it. ...
Significant median partial-onset seizure reduction rates of 23% for 4 mg/day, 26–31% for 8 mg/day and 18–35% for 12 mg/day were reported. Likewise 50 percent responder rates were 29% for 4 mg/day, 33–38% for 8 mg/day and 34–36% for 12 mg/day. Primary generalized tonic–...
Any partial-onset (focal) seizures 15 (100) 23 (100) 9 (100) 32 (100) 47 (100) Partial evolving to secondarily generalized (focal to bilateral tonic-clonic) 8 (53.3) 13 (56.5) 7 (77.8) 20 (62.5) 28 (59.6) Focal seizure frequency per 28 days, median (range) 23.0 (3–384) 11....
(54.0) Age of seizure onset, years (interquartile range) 14 (11–23) Duration of epilepsy, months (interquartile range) 78 (12–180) EEG epileptiform discharges, n (%) 37 (100.0) ASM load (interquartile range) 1.4 (0.6–2.5) FCD side Right side, n (%) 16 (43.2) Left side, n ...