The focal lesion of the liver is usually characterized by the absence of the liver's uptake of radioactive scanning agents. In the focal lesion, the incorporation of 75Se-selenomethionine is related to its vascularity and capacity to met... E Kaplan,M Domingo - 《Seminars in Nuclear Medicine...
Focal nodular hyperplasia is a focal proliferation of benign hepatocytes within the liver. These primary liver masses are relatively common and are often discovered incidentally in asymptomatic patients. Comprehensive radiologic evaluation will provide a confident diagnosis of this benign entity in most pati...
Also there is suppression of liver fatty acid-binding protein, resulting in impaired fatty acid transport in hepatocytes, leading to intracellular fat deposition. Oestrogens act as endogenous genotoxic agents and cause hepatocyte proliferation by somatic mutations in the TCF1 gene [2, 36, 38]. ...