The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J Biol Chem. 1999; 274 :33166–33176. doi: 10.1074/jbc.274.46.33166. [ Cross Ref ]Meighan-Mantha RL, Hsu DKW, Guo Y, Brown SAN, Feng SY, et al. (1999) The ...
Phylogenetically Fn14 is much conserved and there is a 90% homology between the mouse and the human protein (Wiley and Winkles2003). The human Fn14 gene is located at chromosomal position 16p13.3, encodes a type I transmembrane protein of 129 aa that is processed into a mature 102-aa prot...
Gene Information human ... TNFRSF12A(51330) 安全信息 储存分类代码 12 - Non Combustible Liquids WGK WGK 3 闪点(F) Not applicable 闪点(C) Not applicableSigma-Aldrich推荐产品 FXR, GST tagged human GABA B Receptor R1, control peptide for AB1531 Galactose-1-phosphate Uridyltransferase from galactos...
[2] Lefebvre S, Bürglen L, Reboullet S, Clermont O, Burlet P, Viollet L, et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell. 1995;80:155–65. [3] Crawford TO, Pardo CA. The neurobiology of childhood spinal muscular atrophy. Neurobiol Dis. 199...
Fn14 was described in fibroblasts as Fibroblast Growth Factor–inducible-14, an immediate-early response gene to growth factors (Meighan-Mantha et al.1999... Author information Authors and Affiliations IdI-Paz, IIS-Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Madrid, Spain ...
We then investigated TWEAK and Fn14 gene expression in the murine MCAO model of cerebral ischemia. This model produces a very reproducible area of infarct and changes in both the ischemic penumbra region of the ipsilateral hemisphere and the corresponding region of the nonischemic contralateral hemisp...
aRelativeFn14gene expression levels in Basal-like (n = 229), HER2 (n = 158), Luminal A (n = 300), Luminal B (n = 304), Normal-like (n = 106) and non-cancer (n = 113) patient samples from the TCGA BRCA RNA-seq dataset. Box plot depicts the first...
TWEAK binds to Fn14 (fibroblast growth factor-inducible 14), a small (102 amino acids) plasma-membrane-anchored receptor. TheFn14gene is a growth-factor-inducible, immediate-early response gene, and it is highly expressed following tissue injury and in numerous solid tumour types. ...
Gene/Protein Identifier: A003364 (UCSD Signaling Gateway ID)Concentration: 1mg/ml.Formulation: Liquid. In PBS containing 0.02% sodium azide.Purity: ≥95% (SDS-PAGE)Endotoxin Content: <0.1EU/µg purified protein (LAL test; BioWhittaker).Specificity: Binds human and mouse TWEAK.Biological ...
UniProt ID: Q9CR75 Gene/Protein Identifier: A003364 (UCSD Signaling Gateway ID) Concentration: 1mg/ml after reconstitution. Formulation: Lyophilized. Contains PBS. Purity: ≥95% (SDS-PAGE) Endotoxin Content: <0.1EU/µg purified protein (LAL test; BioWhittaker). Specificity: Binds human and ...