因此,FN1和 CD49D基因表現對於口腔鱗狀上皮細胞癌的診斷能力優於SDC2以及 CD44,是具有偵測口腔鱗狀上皮細胞癌潛力的腫瘤標誌。另外,經 統計交叉分析發現,鱗狀上皮細胞癌組織與自體非腫瘤組織之基因 相對表現倍數在各AJCC口腔惡性腫瘤分期之間、致癌不良習癖(菸、 酒與檳榔)接觸史之間無顯著差異存在,若以FN1和CD49...
1 (FN1), integrin α4β1 (ITGA4), syndecan-2 (SDC2), and glycoprotein CD44 in matched OSCC/margin tissues.%Results: Areas under receiver-operating characteristic curves (AUCs) of relative mRNA expression of FN1, ITGA4, SDC2, and CD44 were 0.700, 0.677, 0.513, and 0.549, respectively. ...
Even after long-term expansion on the FN1 motifs surface, hMSC-BM maintained their specifc immunophenotype and continued to express high levels of mesenchymal markers such as CD105, CD73, CD90 and CD44, while lacking the expression of hematopoietic lineage markers (< 1% CD11b, CD34, CD45, ...
[1]Rutnam ZJ,Yang BB.The non-coding 3'UTR of CD44 induces metastasis by regulating extracellular matrix functions[J].J Cell Sci,2012,125(8):2 075-2 085. [2]Castellana B,Escuin D,Peiro G,et al.ASPN and GJB2 Are Implicated in the Mechanisms of Invasion of Ductal Breast Carcinomas[J...
CD44 is an independent prognostic factor in early-stage cervical cancer. The expression of specific cell-adhesion molecule CD44 isoforms (splice variants) is associated with metastatic spread and poor prognosis in human malignan... P Speiser,C Wanner,C Tempfer,... - 《International Journal of Can...