CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation. CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing...
CD20FMC7cholesterolepitopeAccurate diagnosis of lymphoid malignancies is essential for appropriate therapeutic intervention. In conjunction with other diagnostic determinants, immunophenotypic analysis of differentially expressed cell surface markers, such as CD5, CD20, CD23 and FMC7, is useful in the ...
FMC7抗体是一种常用于研究和诊断的单克隆抗体,主要用于检测B细胞恶性肿瘤。它在免疫学研究中有着广泛的应用,特别是在白血病和淋巴瘤的诊断中。这种抗体能够特异性地识别B细胞表面的CD20分子,帮助研究人员和临床医生更好地了解疾病的进展和治疗效果。
A. 典型的免疫表型:CD5(+)、CD10(+)、CDl9(+)、FMC7(-)、CCND1(+) B. 老年患者比年轻患者多发 C. 男性患者比女性患者多发 D. 13q14-的缺失是最常见的慢性淋巴细胞白血病染色体异常,单独出现是预后良好的标志 E. 17p-的出现是慢性淋巴细胞白血病最差的预后因素,但对氟达拉滨及CD20单抗反应良好...
徐赢东主治医师 血液科 中国医科大学附属第一医院休息中 2021年08月28日 第1次提问 请问血液科流式细胞检测报告中P2占有核细胞85.5%,为成熟淋巴细胞,其中80.6%表达CD19.CD20.CD22.cD23.FMC7.kαppα,不表达CD7.CD5.CD34,CD38.CD10.CD200.lαmbdα,为单克隆成熟小B淋巴细胞是什么意思? 2021年08月28日...
幼淋巴细胞白血病的免疫学特点是A.多数病例属T细胞性B.单抗FMC7几乎100%阳性C.CDl9、CD20阳性率低D.CDl03、CD5阳性E.无玫瑰花形成细胞存在请帮忙给出正确答案和分析,谢谢! 网友 1 最佳答案 回答者:网友 正确答案担屋或大景航:B我来回答 提交回答 重置等...
基因别名:B1; Bp35; CD20; CVID5; LEU-16; MS4A1; MS4A2; S7 UniProt ID:(Human) P11836 Entrez Gene ID:(Human) 931 功能 epidermal growth factor receptor bindingprotein bindingMHC class II protein complex bindingtransporter 参与通路 humoral immune responseB cell proliferation...
FMC7 antigen expression on normal and malignant B-cells can be predicted by expression of CD20. Cy- tometry 1998;34:71-74.Hu¨ bl W, Iturraspe J, Braylan RC. FMC7 antigen expression on normal and ma- lignant B-cells can be predicted by expression of CD20. Cytometry. 1998;34: ...
FMC7 is an epitope of CD20. Blood 2008; 111: 2492; author reply 2493- 2494.Deans JP, Polyak MJ. FMC7 is an epitope of CD20. Blood. 2008; 111: 2492-94.Deans JP, Polyak MJ. FMC7 is an epitope of CD20. Blood. 2008;111:2492; author reply 2493-2494....
FMC7 antigen expression on nor- mal and malignant B-cells can be predicted by expression of CD20. Cytometry 1998; 34: 71-74.Hubl W, Iturraspe J, Braylan RC. FMC7 antigen expression on normal and malignant B-cells can be predicted by expression of CD20. Cytometry. 1998;34:71-74....