Fluorouracil Cream USP should be applied preferably with a nonmetal applicator or suitable glove. If Fluorouracil Cream USP is applied with the fingers, the hands should be washed immediately afterward. Actinic or Solar Keratosis: Apply cream twice daily in an amount sufficient to cover the lesions...
The dose of Efudex topical is to apply a small amount of the cream to the area that is to be treated, once or twice daily after cleansing. Treatment lasts 2-6 weeks depending on the condition being treated. Wash hands immediately afterward. Do not use other prescription or over-the-counte...
1%, 2%, 5% cream or 2%, 5% solution: Apply 2 times a day in an amount enough to cover the lesions; continue until the inflammatory response reaches the erosion stage, then discontinue use -Duration of therapy: 2 to 4 weeks; complete healing of the lesions may not be evident for 1 to...
respectively. Studies with a 5% topical solution yielded an oral LD50of 214 mg/kg in rats and 28.5 mg/kg in dogs, corresponding to 10.7 and 1.43 mg/kg of fluorouracil, respectively. The topical application of the 5% cream