Apply cream twice daily in an amount sufficient to cover the lesions. Medication should be continued until the inflammatory response reaches the erosion stage, at which time use of the drug should be terminated. The usual duration of therapy is from 2 to 4 weeks. Complete healing of the lesio...
Apply cream or solution twice daily in an amount sufficient to cover the lesions. Medication should be continued until the inflammatory response reaches the erosion stage, at which time use of the drug should be terminated. The usual duration of therapy is from 2 to 4 weeks. Complete healing ...
The oral LD50for the 5% topical cream was 234 mg/kg in rats and 39 mg/kg in dogs. These doses represented 11.7 and 1.95 mg/kg of fluorouracil, respectively. Studies with a 5% topical solution yielded an oral LD50of 214 mg/kg in rats and 28.5 mg/kg in dogs, corresponding to 10.7 a...
Specifically, the developed nanofilms seem very well suited for topical skin cancer treatment, where we would use the SMNPs for the incorporation and controlled release of 5-FU. At the same time, these NPs (with superparamagnetic properties) would enable us to track and evaluate this drug ...
hydrophobic drugs can be loaded into ZIF-8, and drug ligands or linkers can be complexed with the outer surface of the MOFs for combination or multimodal therapy of cancer [20]. To facilitate topical delivery on the skin, the carrier must be mixed with a base such as a cream, gel or ...