COMPOSITIONS FOR AND METHODS OF IMPROVING FLUID FLUX IN THE BRAINThe present disclosure provides compositions for and methods of preventing protein aggregation, removing protein aggregates, and improving fluid flux in the brain.ASOKAN, ARAVINDMITCHELL-DICK, AARON...
Directly related to meningitis is encephalitis, and it's possible to have the two diseases together, a condition known as meningoencephalitis. Encephalitis also inflames the brain, often because of the herpes simplex virus. This condition is diagnosed by examining the patient's brain fluid. Sympto...
The authors report a wide and updated revision of hydranencephaly, including a literature review, and present the case of a patient affected by this condition, still alive at 36months.Hydranencephaly is an isolated and with a severe prognosis abnormality, affecting the cerebral mantle. In this co...
CSF from the subarachnoid space moves rapidly into the brain along paravascular routes surrounding penetrating cerebral arteries, exchanging with brain interstitial fluid (ISF) and facilitating the clearance of interstitial solutes, such as amyloid beta, in a pathway that we have termed the "glymphatic...
Cerebrospinal fluid (CSF), clear, colourless liquid that fills and surrounds the brain and the spinal cord and provides a mechanical barrier against shock. Formed primarily in the ventricles of the brain, the cerebrospinal fluid supports the brain and pr
HOW DOES ANESTHESIA AFFECT VARIOUS LEVELS OF EXPERIMENTAL TRAUMATIC BRAIN INJURY? The use of anesthetics is a well-known treatment for severely injured patients. In the present study we tested the pathophysiology of several levels of inj... BM Efrat,M Tamar,R Gennady,... - 《Journal of Innova...
Two subsets of dendritic cells are present in human cerebrospinal fluid Little is known about the presence of dendritic cells in the human CNS. To investigate the occurrence of dendritic cells in the CSF, paired blood/CSF sampl... P Mikhail,Huang Yu-Min,K Vasilios,... - 《Brain A Journal...
All data needed to evaluate the conclusions in the paper are present in the paper and/or the Supplementary Materials. Additional data available from authors upon request. Source data are provided with this paper. References Xie, L. et al. Sleep drives metabolite clearance from the adult brain....
Hydrocephalus is a common disorder caused by the buildup of cerebrospinal fluid (CSF) in the brain. Treatment typically involves the surgical implantation of a pressure-regulated silicone tube assembly, known as a shunt. Unfortunately, shunts have extremely high failure rates and diagnosing shunt malf...
Levels of PLCγ, a phospholipase C (PLC) isozyme, were significantly increased in the cytosol in the injured left cortex (LC) at 5, 30 and 120 min after brain injury. In the same site, although levels of membrane PLCγ did not alter at 5 and 30 min, they were found to be decrease...