Various reduced-intensity conditioning (RIC) regimens are used to decrease toxicity while providing comparable outcomes to myeloablative regimens. We compared toxicity and outcomes between two RIC regimens, fludarabine with melphalan (Flu-Mel) and fludarabine with treosulfan (Flu-Treo),...
Our previous research indicated that a reduced-intensity conditioning regimen (fludarabine and melphalan at 100 mg/m2) was useful in allogeneic hematopoietic cell transplantation (HCT) for patients with lymphoma. This retrospective study evaluated the reduced-intensity conditioning regimen in allogeneic HCT...
Median age at HSCT was 28 months (range: 4 months-14 years).The preparative regimen consisted of fludarabine, melphalan and antithymocyte globulin. 8 patients received stem cell from healthy full HLA-matched siblings, 7 patients from HLA matched other relative (four patients from parents, two ...
Here we report the retrospective analysis of data from 27 patients with mature T-cell lymphoma treated with salvage allogeneic haematopoietic cell transplantation at the City of Hope, Duarte, CA, USA, using a reduced-intensity fludarabine/melphalan conditioning regimen between the years 2001 and 2008...
Choosing a Reduced-Intensity Conditioning Regimen for Allogeneic Stem Cell Transplantation, Fludarabine/Busulfan versus Fludarabine Melphalan: A Systematic Review and Meta-Analysis 2019, Biology of Blood and Marrow Transplantation Citation Excerpt : The study was performed in accordance with the recommendations...
Favorable Survival Outcomes in AML Patients Undergoing Allogeneic Hematopoietic Cell Transplant with Fludarabine/Melphalan-Conditioning with Tacrolimus/Sir... Salhotra:Gilead:Research Funding;Kura Oncology:Research Funding;Jazz Pharma:Research Funding;BMS:Research Funding;OrcaBio:Research Funding;Sanofi:Speakers...
Disease recurrence is known to be particularly high in patients with JMML given an allograft, but the percentage of relapse seems to be higher than that reported using the busulfan/cyclophosphamide/melphalan regimen [32]. However, due to the very low number of JMML patients, no conclusions can ...
Reduced-intensity conditioning for allogeneic hematopoietic stem cell transplantation with fludarabine and melphalan is associated with durable disease con... We retrospectively evaluated the outcome of reduced-intensity conditioning (RIC) followed by allogeneic hematopoietic stem cell transplantation (HCT) in ...
Substitution of cyclophosphamide and busulfan by fludarabine, treosulfan and melphalan in a preparative regimen for children and adolescents with Shwachman... Allogeneic hematopoietic stem cell transplantation (HSCT) is the only definitive treatment for severe bone marrow dysfunction and clonal disorders in...
underwent an initial allogeneic HCT between January 2008 and December 2019, we excluded 2924 patients who received conditioning regimen other than fludarabine with reduced-intensity or myeloablative busulfan, 253 patients who received additional melphalan, and 5 patients who received TBI > 4 Gy (...