Sequencing Of The Flg2 Gene In Patients With Atopic Dermatitis And Eczema Herpeticum In A Population Of European Descent.AnaphylaxisFoodAllergyFood-induced anaphylaxis (FIA) is a serious allergic reaction that may cause death rapidly in otherwise healthy individuals. There is no universal agreement on...
gene and related diseases were reviewed in this article．［Key words］FLG；atopic dermatitis；psoriasis；ichthyosis vulgaris 中间丝蛋白相关基因（Filaggrin，FLG）的翻译表达产物Profilaggrin是存在于人表皮角质形成细胞（keratinocyte，KC）内的一种酸性或中性蛋白，参与角质形成细胞终末分化时细胞间交叉联结膜的形成，...
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In Copenhagen, FLG mutation increased the risk of eczema in infants. Infantile eczema linked to cat ownership in children with gene mutation Two loss-of-function mutations of FLG, RS01X and 2282de14, now have been shown to be responsible for a lack of filaggrin in the upper epidermis among...
In the FLG-corrected clone (HEECOR), the presence of keratohyalin granules was reinstated together with the complete recovery of FLG expression, as was expected from the protein sequences (Supplementary Table S1). FLG regulates epidermal differentiation gene and protein expression Next, the ...
上海交通大学 博士学位论文 FLG基因功能缺失突变及其疾病相关性研究 姓名:***申请学位级别:博士 专业:皮肤病与性病学 指导教师:**荣 201205 上海交通大学博士学位论文 FLG基因功能缺失突变及其疾病相关性研究 摘要 目的:分析中间丝相关蛋白基I因(Filaggrin,FLG)功能缺失突变与特应性 皮炎(atopicdermatitis,AD)和单纯...
Loss-of-function FLG mutations are associated with reduced history of acne vulgaris in a cohort of patients with atopic eczema of Bangladeshi ancestry in East Londondoi:10.1093/ced/llae185BACKGROUND. Acne vulgaris (AV) is the eighth most common nonfatal disease globally. Previous work identified...
Previous work identified an association between AV and increased filaggrin (FLG) protein expression in the follicular epidermis, but further work did not find a clear link between loss-of-function (LoF) FLG gene mutations and protection from AV. OBJECTIVES. To explore any association between AV ...
Variations In The FLG2 Gene Are Associated With Eczema Herpeticum In Populations Of European And African DescentEPEC TirITIMSHP1/2cytokinesmacrophagesAcute anaphylaxis (AAN) is rare in children and is difficult to diagnose especially in cases of inaugural manifestation. A wide range of disorders are...