Groups C鈥揊 are two-protein systems, composed of a monooxygenase and a flavin reductase. Groups G and H comprise internal monooxygenases that reduce the flavin cofactor through substrate oxidation. Recently, many new flavin-dependent monooxygenases have been discovered. In addition to posing basic ...
Cover Feature: Flavin-Dependent Monooxygenases NotI and NotI′ Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides (ChemBioChem 17/2020)spirocyclenotoamideflavin monooxygenasebiosynthesisalkaloidsdoi:10.1002/cbic.202000548John Wiley & Sons, LtdChemBioChem...
Xanthone-containing natural products display diverse pharmacological properties. The biosynthetic mechanisms of the xanthone formation have not been well documented. Here we show that the flavoprotein monooxygenase FlsO1 in the biosynthesis of fluostatins not only functionally compensates for the monooxygenase...
Contig_25748 0.0154 69.81 0.0414 7.62 0.0319 4.53 gi|297139712|ref|NP_001171912.1|flavin-dependent monooxygenase FMO2 [Bombyx mori] Contig_3261 0.0243 56.39 0.0054 21.08 0.0396 11.69 gi|153791757|ref|NP_001093275.1|myo-inositol oxygenase [Bombyx mori] Contig_19228 0.0154 45.96 0.0024 8.76 0.0410 5.37...
et al. Identification of a hotspot residue for improving the thermostability of a flavin-dependent monooxygenase. ChemBioChem 20, 3020–3031 (2019). Article CAS PubMed Google Scholar Download references Acknowledgements We thank the Thailand Science Research Innovation and NSRF via the Program ...
Coq6p is a peripheral membrane protein that localizes to the matrix side of the inner mitochondrial membrane. Based on sequence homology to known proteins, we suggest that COQ6 encodes a flavin-dependent monooxygenase required for one or more steps in Q biosynthesis. 展开 ...
Discusses the isolation of Coenzyme Q6 (Coq6) gene by functional complementation. Inability of the Coq6 mutants to grow on nonfermentable carbon sources; Incorporation of the Coq6 polypeptide into the mitochondria; Localization of the protein to the matrix side of the inner mitochondrial membrane.年...
The application model of Internet of things technology in greenhouse vegetable was initially established to realize the automatic collection, transmission and control of environment data in greenhouse.doi:10.1007/s11071-014-1633-5QIN LijieYANG ZhongyanWANG YanlingAgriculture Network Information...
CJ77 capable of utilizing various sulfonamides as a sole carbon source was isolated from a composting facility. Genome and proteome analyses revealed that a gene cluster containing a flavin-dependent monooxygenase and a flavin reductase was highly up-regulated in response to sulfonamides. Biochemical ...
CYP3A, cytochrome P450 3A; FMO, flavin-containing monooxygenase; HLM, human liver microsome. expression data demonstrate that there is a clear transition of the predominant CYP3A isoform from the fetal population (CYP3A7) into adulthood (CYP3A4). These results generally confirm the pattern of age...