FITC-Dextran (MW 2000000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption. Storage: protect from light. In Vivo: Guidelines (Following is our recommended protocol. This protocol only provides...
Oral administration of fluorescein isothiocyanate dextran (FITC-d) has been used as an indicator for intestinal permeability in poultry research for several years. Under healthy conditions, tight junctions in the intestinal wall will not allow the 4-6kDa FITC-d to enter the bloodstream. Detection ...
描述FITC-Dextran 是由 FITC 偶联葡聚糖形成的一种标记物。FITC-Dextrans 是由不同长度的支链葡萄糖分子组成的被标记的多糖,分子量从 4-70 kDa 不等,可根据所使用的葡聚糖的大小来测定血脑屏障的溶质、离子和蛋白质渗透性。 相关类别 研究领域 >> 其他 ...
FITC - Dextran (MW 4000) is formed by FITC coupling glucan a marker (4 kDa). FITC - Dextran is composed of different length of branched chain glucose molecules is marked polysaccharide, can according to the size of the glucan used to determine the blood brain barrier, ion permeability and ...
FITC-Dextran is a marker consisting of coupling fluorescein-isothiocyanate to dextran. FITC-Dextran is used to determine solute, ion and protein permeability of the blood-brain barrier (BBB). ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商,致力于为广大科研、商业实验室的科学研究者提供高...
To investigate the influence of the dose in the FITC-Dextran 4kDa (FD-4) permeability test in an obese mouse model, we tested the bodyweight dose regimen and a lean body mass-based dose regimen in high fat diet (HFD) mice and low fat diet (LFD) mice. We
dextran fixes well in cells and tissue when treated with formaldehyde or glutaraldehyde and is primarily used for studying permeability and transport in cells, vessels and tissues. Spectral data:Excitation is best performed at 493 nm and fluorescence measured at 520 nm. ...
–70 kDa and can be used to determine solute, ion and protein permeability of the BBB based on the size of the dextran used. Because FITC-dextrans are exogenous and can be administered at discrete intervals, in contrast to endogenous molecules like IgG and albumin, they can provide valua...
Fluorescein isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier PermeabilityBlood-brain barrier, FITC-dextran extravasation, brain capillariesThe blood-brain barrier (BBB) is formed in part by vascular endothelial cells that constitute the capillaries and microvessels of the ...
FITC-Dextran 是将绿色荧光染料 FITC(Fluorescein Isothiocyanate)通过化学方式与葡聚糖分子上的羟基或氨基进行共价连接制备而成的荧光探针,具有良好的水溶性、生物相容性和强烈绿色荧光发射信号,广泛用于细胞生物学、分子追踪、血管渗透性评估等研究领域。 一、基本信息 ...