近期,美国圣路易斯华盛顿大学医学院Erica K. Barnell团队开发了多靶点粪便RNA(mt-sRNA)检测工具ColoSense,可用于45岁以上人群的CRC筛查。 在涉及8920名参与者的前瞻性3期临床试验中,mt-sRNA可以识别36例经结肠镜确诊CRC患者中的34例,检测敏感性高达94.4%,远高于常规粪便免疫化学检测(FIT)结果(94% vs. 78%;P=...
OBJECTIVES: To evaluate a two-tier reflex guaiac-based faecal occult blood test (gFOBT)/faecal immunochemical test (FIT) algorithm in screening for colorectal cancer. SETTING: Fourth screening round in NHS Tayside (Scotland). METHODS: gFOBT were sent to 50-74-year-olds. Participants with five...
Introduction Several bowel cancer screening programmes, including the NHS Bowel Cancer Screening Programme (BCSP) in England, use a guaiac-based faecal occult blood test (gFOBt). Seasonal variations in gFOBt positivity have been reported, with lower positivity in the warmer spring and summer months...
were widely interpreted as a recommendation for a traditional guaiac faecal occult blood test (gFOBT), a method which has relatively poor sensitivity (approximately 75%) [8,9,10] in symptomatic populations and which is no longer widely available in the UK NHS, outside the screening programmes....
were widely interpreted as a recommendation for a traditional guaiac faecal occult blood test (gFOBT), a method which has relatively poor sensitivity (approximately 75%) [8,9,10] in symptomatic populations and which is no longer widely available in the UK NHS, outside the screening programmes....
Being due for screening was defined as having no evidence in the electronic health record (EHR) of either (1) a fecal test in the previous year, (2) an order for a fecal test in the previous 6 months, (3) a flexible sigmoidoscopy in the previous 4 years, (4) a colonoscopy in ...
Socioeconomic variation in uptake of colonoscopy following a positive faecal occult blood test result: a retrospective analysis of the NHS Bowel Cancer Scr... Bowel cancer is a serious health burden and its early diagnosis improves survival. The Bowel Cancer Screening Programme (BCSP) in England sc...
Fit-test failure rates across all masks were not found to be significantly different between genders when comparing outcomes from seven NHS hospitals. A similar conclusion was reached by Foreland et al., investigating outcomes for 701 fit-tests in the Norwegian smelting industry, a small study comp...
Keywords: colorectal cancer; external quality assessment (EQA); faecal immunochemical test (FIT); faecal-like matrix Corresponding author: Sally C. Benton, NHS Bowel Cancer Screening Programme Southern Hub, Royal Surrey County Hospital, Guildford, England, UK; and Berkshire and Surrey Pathology Service...
release employees to attend a pop-up lung screening clinic. Effects of changes: Intervention required in over half of attendees (see Tables 1 and 2). Lessons learnt: Workers cited peer encouragement and clinic accessibility (permission, proximity, paid work time) as integral to attendance. The ...