(1990) First trimester maternal serum in alpha-fetoprotein and human chorionic gonadotrophin screening for chromosome defects. Fetal Diag. Ther. 7, 123-131.Milunsky, A. , Wands, J. , Brambati, B. , Bonacchi, L. , Currie, K. ( 1988 ). First trimester maternal serum alpha-fetoprotein ...
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First TrimesterWhat are the first symptoms of pregnancy? Missing a period is usually the first signal of a new pregnancy, although women with irregular periods may not initially recognize a missed period as pregnancy. During this time, many women experience a need to urinate frequently, extreme ...
Materials and methods: We retrospectively searched the patient charts of our hospital for first trimester Down syndrome screening test results. PAPP-A levels less than 5th percentile were considered as predictive of SGA infants. Results: Low PAPP-A levels were associated with SGA infants, sensitivity...
These samples were collected as part of a study in which the performance of a model for first trimester screening in the Netherlands was studied prospectively [11]. Control samples had no co-morbidities, such as systemic lupus erythematosus, diabetes mellitus or antiphospholipid syndrome, no ...
Screening for aneuploidy has traditionally been reserved for women of advanced maternal age. More recent advances in serum screening and ultrasound technology have allowed women of all ages to be offered screening in the second and even first trimester. These methods and their effectiveness are discuss...
Results: First-trimester screening was associated with lower screening and live-born Down syndrome costs versus second-trimester serum screening. Total Down syndrome screening costs were 29.1% lower with first-trimester screening. Conclusion: In this hypothetic model, combined first-trimester screening ...
Screening of maternal serum for fetal Down's syndrome in the first trimester. N Engl J Med. 1998;338:955–61. 12. Keikkala E, Vuorela P, Laivuori H, Romppanen J, Heinonen S, Stenman UH. First trimester hyperglycosylated human chorionic gonadotrophin in serum – a marker of early-...
The distribution of the first-trimester combined screening test risk categories according to maternal age (<35≥ years). Genetic analyses were performed in 58.8% of cases (180/306) of which 95 were CVS, 81 were amniocentesis and four were post-natal or post-abortion samples. Among these, 66...
Results Trio family information A total of 17 pregnant women were recruited. Among these, 14 singleton pregnant women provided blood samples in the first trimester, from 7 to 12+5 weeks. Only two singleton pregnant women had blood collected after 13 weeks. One woman provided a blood sample at...