Results in schizophrenia suggest that glx concentrations are different for each stage of the illness. Although results in ARMS subjects are not consistent, the majority of studies show increased glx,64, 65, 66, 67, 68 whereas a few report decreased69,70 or normal71,72 values (see Table 2A)...
Single-cell transcriptomics of the human parasite Schistosoma mansoni first intra-molluscan stage reveals tentative tegumental and stem-cell regulators Carmen L. Diaz Soria, Teresa Attenborough, Zhigang Lu, Santiago Fontenla, Jennie Graham, Christopher Hall, Sam Thompson, Toby G. R. Andrews...
Higher expression (P < 0.05) of Pgp genes, except Pgp-4, was observed in L1 stage larvae from the R isolate. Our findings suggest that the L1 stage can be potentially used for anthelmintic resistance characterization through monitoring of different P-glycoproteins gene expression. These results ...
Finally, we derived a consensus gene-set to identify OT in treated KTRs, by analysing IS-drug-adjusted expression levels for all published signature genes. Implications of all the available evidence When drug-adjustment is not performed at the signature development stage, the resultant signatures ...
Pigeonpea (Cajanus cajan (L.) Millsp) is one of the major grain legume crops of the tropics and subtropics, but biotic stresses [Fusarium wilt (FW), sterility mosaic disease (SMD), etc.] are serious challenges for sustainable crop production. Modern geno
The earliest stages of development in most animals, including the few mammalian species that have been investigated, are regulated by maternally inherited information. Dependence on expression of the embryonic genome cannot be detected until the mid two-cell stage in the mouse, the four-cell stage ...
At this stage, the proton released into bulk solvent by the reaction nucleophile24 is transferred to the N3 atom on the C358 nucleobase, either via specific proton transfer pathways, as previously proposed24 (an illustration of one pos- sible transfer pathway is reported in Supplementary Fig. ...
However, the biological consequences of these fixed SNPs are unclear at this stage. All the concerned genes encode enzymes which are involved in a series of reactions that we extracted using metabolic databases [47]. The Fig. 6 reports one of the most significant reconstructed metabolic network ...
19. M2 and the phosphate backbone of C358 deprotonate the reaction nucleophile for catalyzing the scission of the 5′-splice-site. At this stage, the proton released into bulk solvent by the reaction nucleophile24is transferred to the N3 atom on the C358 nucleobase, either via specific ...
The ability of cART to undo the HIV induced metabolic dysregulation is unclear and under-investigated. Using targeted metabolomics and multiplex immune biomarker analysis, we characterized plasma samples obtained from 18 untreated HIV-1-infected adult patients and compared these to a non-HIV infected ...