First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer 机译:PF-05212384(PKI-587)是晚期癌症患者的小分子,静脉内PI3K和mTOR双重抑制剂的首次人体研究 著录...
First-in-human study The BIOGUIDE-X study, led byLucas VitzthumandMurat Surucufrom Stanford, andDaniel Changof the University of Michigan, included two sequential groups of participants, all of whom had at least one FDG-avid targetable tumour in the lung or bone. The study in cohort I confi...
Microsurgery of the retina would be dramatically improved by instruments that offer supra-human precision. Here, we report the results of a first-in-human study of remotely controlled robot-assisted retinal surgery performed through a telemanipulation de
A first-in-human clinical trial of a fully human, Fc-engineered IgG1 monoclonal antibody targeting integrin α5β1 was conducted to evaluate tolerability, maximum tolerated dose, pharmacokinetics, pharmacodynamics and preliminary anti-tumor activity. Escalating doses of PF-04605412 were given IV on ...
A first-in-human Phase 1 study was initiated to determine a recommended dose and schedule for margetuximab in patients with any relapsed HER2-overexpressing carcinoma. Pharmacokinetics, immunogenicity, and antitumor activity were also evaluated, in addition toex vivo ADCC analyses to confirm margetuxi...
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects Author links open overlay panelXin-Mei Yang a #, Yang Yang b #, Bu-Fan Yao c #, Pan-Pan Ye a, Yan Xu d, Shao-Ping Peng b, Yu-Mei Yang b, ...
This is a first-in-human study with TAS-119, an Aurora A kinase (AurA) inhibitor. Patients with advanced, refractory, solid tumours were enrolled into 5 dose escalation cohorts (70–300 mg BID, 4 days on/3 days off, 3 out of 4 weeks or 4 out of 4 week
Big fast food chains in New York City have started to obey a first-of-its-kind rule requiring them to post calorie counts right on the menu. 出自-2016年6月听力原文 I first began to investigate the basis of human motivation—and how people persevere after setbacks—as a psychology graduate...
a你在那个班 You in that class[translate] a我们结婚两年了 We married for two years[translate] a你们应该能很容易查找到利用1个代码运行很多帐号的人 You should be able very easy to search the human who uses 1 code movement very many account numbers[translate] ...
alast month I was in Beijing 上个月我在北京[translate] aHuman and animal mating 正在翻译,请等待...[translate] ahe comes into the room 他进入屋子[translate] awe should think about this a bit longer 我们应该长期考虑[translate] aa total score out of 110 一个总比分从110当中[translate] ...