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Most of the known AHTPs searched in this database have been verified in reported studies, and they are usually tripeptides with less than 10 amino acids; the top 50 AHTPs with the highest activity were chosen to i...
The specific (2R, 4aS, 4aS)-stereochemistry around the fused morpholine ring was required for activity. The morpholine ring oxygen can be replaced with carbon, but at the expense of solubility, and the two methyl substituents proved to be optimal. The benzisoxazole fluorine atom was also ...
There are no longitudinal studies comparing growth of off- spring of DM1 and DM2 women, which might be crucial to formulate preventive strategies in these high-risk groups. Data on height of offspring from women with diabetes are also lacking; such data may help to identify the importance of ...