其实是一种特殊的First-in-class,但又有质的不同,普通的First-in-class容易被Me-too,但是Me-only不会被Me-too。 pipeline(研发管线): 通常是指某医药公司或药物研究机构一批正处开发阶段的药物,包括临床前、临床研究等。 IND (...
在中国近年来风起云涌的创新药大潮中,有些公司通过fast follow全球的热门靶点来开发新药项目,有些通过license in的方式获得first-in-class/best-in-class的候选药物,可谓各显神通。在众多创新药研发公司中,有这么一家公司,从早年研发、生产和销售疫苗,到如今开发出自有免疫调节技术平台并建立原创免疫疗法产品管线,以十...
在中国近年来风起云涌的创新药大潮中,有些公司通过fast follow全球的热门靶点来开发新药项目,有些通过license in的方式获得first-in-class/best-in-class的候选药物,可谓各显神通。在众多创新药研发公司中,有这么一家公司,从早年研发、生产和销售疫苗,到如今开发出自有免疫调节技术平台并建立原创免疫疗法产品管线,以十...
gradually developed into a set of guangxi coastal areas of medical, scientific research, teaching, first aid, prevention, health care and so on many functions in an organic whole, medical technical force is rich, strong comprehensive strength, large scale of the modernized level of first-class ...
Beijing grants first catering business license to robot chefs Video 15:09, 11-Oct-2024 Central government approval integral to the tulku reincarnation system Video 10:41, 24-Dec-2024 China's homegrown snow gear and infrastructure driving industry growth Video 21:10, 31-Dec-2...
GSK3036656 (ganfeborole) is a first-in-class benzoxaborole inhibiting the Mycobacterium tuberculosis leucyl-tRNA synthetase. Here, in this phase 2a, single-center, open-label, randomized trial, we assessed early bactericidal activity (primary objective) and safety and pharmacokinetics (secondary ...
Using small-molecule drug-design approaches, we generated and validated PXS-5505, a first-in-class highly selective and potent pan-lysyl oxidase inhibitor. We demonstrate in vitro and in vivo that pan-lysyl oxidase inhibition decreases chemotherapy-induced pancreatic tumor desmoplasia and stiffness, ...
sintering. The main challenge here is to fill the polymer with the highest possible weight fraction of ceramic particles, while maintaining the properties needed for the 2PP process. In this paper, the development of this new class of resin is introduced and first results of printed parts are ...
FDA free international sales license is not only the highest level of the United States FDA certification, and WTO (WTO) approved the highest pass certification about food and drug, only required by the FDA and the world trade organ...
medical conditions, including, but not limited to, New York Heart Association (NYHA) class III or IV congestive heart failure, history of congenital prolonged QT syndrome, uncontrolled infection, active hepatitis B, hepatitis C or human immunodeficiency virus (HIV), or other significant co-morbid ...