The company’s lead BioPYM, FZ002, is an investigational new drug (IND)-ready candidate targeting the antibiotic-resistant superbug Clostridioides difficile, which is the most prevalent cause of nosocomial infe
Now scientists know that the overuse of antibiotics can cultivate drug-resistant bacteria that are dangerous to human health. Among debates over what kinds of restrictions should be put in place, figuring out how antibiotic-resistant bacteria evolve and make their way to humans remains an area of...
STAT Reports:The revitalization of the antibiotic drug pipeline Pan-resistant C. auris was first detected in 2019 in people who developed resistance while being treated with antifungal drugs. What makes these newly reported cases more concerning is the fact none of the people had been treated wi...
A drug, developed by the researchers, works by targeting Mycobacterium tuberculosis' defenses rather than the bacteria itself and it can also take out its increasingly commonly antibiotic resistant strains. The research funded by the Medical Research Council has been published today in the Journal of ...
In the livestock sector, resilience is an active area of investigation, particularly in the face of the numerous challenges stemming from high-productivity systems [6,7]. These challenges include concerns about animal welfare, the emergence of antibiotic-resistant bacteria posing risks to human health...
to 4 phyla, 34 genera and 56 species, with 17 strains representing putative new taxa. The Gram-negative cave bacteria (Proteobacteria and Bacteroidetes) were more resistant to the great majority of antibiotic classes than the Gram-positive ones (Actinobacteria, Firmicutes). More than 50% of the...
Antibiotic-resistant bacteria rampant in Dhaka’s water sources: Study A recent study by researchers from Jahangirnagar University’s Department of Microbiology has uncovered a concerning prevalence of antibiotic-resistant bacteria in eight distinct water sources across Dhaka and Savar. The findings, part...
Background Multidrug-resistant organisms (MDRO) are a threat throughout the world due to antibiotic overuse and cross- transmission [1]. Infections due to MDRO increase morbidity and even mortality among inpatients. Intensive care units (ICU) are the wards where antibiotic resistance and antibiotic ...
Our study may also be helpful for generating the baseline data for the emergence of multidrug-resistant bacteria related to egg contamination. Because the prevalence of occurrence of antibiotic resistance is increasing, the use of antibiotics for the treatment of infection must be limited in the ...
Interestingly, only abyssomicin C and its atrop stereoisomer show antibiotic activity against Gram-positive bacteria, including MDR S. aureus.26 An additional example of a new chemical class discovered by screening new taxa is represented by thuggacins (Figure 1), which are thiazole-containing ...