In particular, v8HS1 shows generally superior performance relative to v7 (an average 2.3-fold reduction in off-target editing with little or no reduction in on-target editing across all eight sites tested), and we recommend using v8HS1 in preference to v7....
An avulsion fracture of the distal phalanx without DIP joint dislocation may be treated by use of an orthosis with the joint in extension. If there is an avulsion fracture with volar subluxation of the distal phalanx, reduction (closed or open) and internal fixation are considered. These ...