Single-cell RNA-seq has been established as a reliable and accessible technique enabling new types of analyses, such as identifying cell types and studying spatial and temporal gene expression variation and change at single-cell resolution. Recently, single-cell RNA-seq has been applied to developin...
Rga4, one of the nine RhoGAPs present in the fission yeast, is a key factor in the control of cell polarity and morphogenesis by negatively regulating the activity of the essential Rho GTPase Cdc42. We have demonstrated that Rga4 is also a GAP for Rho2 GTPase, which acts upstream of ...
a sort of fingerprint for Earth's atmosphere ininfrared light, which shows the presence of key molecules in the search for habitable worlds. This includes the simultaneous presence
free-living prokinetoplastid species, but until recently none were known. However, in a recent comparative transcriptomic survey of Euglenozoa we showed that free-living flagellate clones PhF-6 and PhM-4 were related to Prokinetoplastina16. Analysis of their transcriptomes showed that...
polarity in the epithelial cells by the Hippo pathway [51], its primary inhibitor, mainly by phosphorylation and proteasomal degradation, preventing nuclear entry. Once in the nucleus, YAP binds to members of the TEAD (Transcriptional Enhanced Associate Domain) transcription factors that possess a DNA...
localization of the dye molecules, in the nano-clay surface or the basal space. The nano-clay-additives-natural dyes bond will be different depending on the incorporation moment of all the additives in the synthesis process. For this reason, the aim of the present work was to know the best...