"We made the observations that T cells from patients with rheumatoid arthritis have low-performing mitochondria, and by screening the cells for their mitochondrial products, we found that the rheumatoid arthritis T cells lack the amino acid aspartate," explains Dr. Weyand. Through a series of expe...
Canakinumab is a fully human anti-interleukin IL-1beta monoclonal antibody, being investigated for the treatment of rheumatoid arthritis (RA). This multicenter, phase II, randomized, double-blind, placebo-controlled, parallel-group, dose-finding study investigated the efficacy and safety of canakinumab...
Chronic or acute inflammation can contribute to a range of ailments—some potentially deadly—including stroke, respiratory and heart disease, cancer, arthritis, asthma, dementia, multiple sclerosis, and diabetes. In May, a study by Dr. Kate Lawlor and collaborator Professor Vince James (WEHI) publ...
“We’re aiming to meet a critical unmet need in prostate cancer treatment,” says Dr. Dan Mercola, who has developed biomarker tests to enhance diagnosis and prognosis. Behind him is a dramatically enlarged image of biopsy tissue. Photo: Steve Zylius (PhysOrg.com) -- Dr. Dan Mercola has...
In clinical practice, it is found that autoimmune thyroid disease often additionally occurs with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). In addition, several studies showed that eye-specific autoimmune diseases may have a strong relationship with systemic autoimmune diseases. We...
Eosinophilia was seen in 26 of 293 patients with fibromyalgia (8.9%), 3 of 182 patients with rheumatoid arthritis (1.65%), and none of 12 patients with scleroderma, but the low prevalence might be explained by the frequent use of corticosteroids among these patients [99]. A recent study ...