Provided is a filtration method for the step of removing viruses in a process of producing a protein preparation during which an intermediate protein preparation with a high protein concentration flows at high pressure to a virus removal filter. The filtration method employs a virus removal filter ...
The method saves time, allows conjugation of less than 1mg protein and produces conjugates better than those obtained by the current methods. Although the present technique has been applied on some common conjugation methods, it provides a potentially general method, and may further be expanded for...
The filtration method according to the present invention increases biological durability of a product being filtered and is characterized in that the product is filtered through a diatomaceous earth filter the filtering layer of which are floated on the filtering candle surfaces in a sequence and grade...
For this method, it is important that the isolated samples are of great purity, as contaminations will lead to false positive results. Gel filtration allows the separation of proteins and protein complexes by size, as published for the ripoptosome (Feoktistova et al., 2011; Tenev et al.,...
One effective method of optimizing wash liquor consumption is countercurrent washing because the wash liquid is reused in multiple washing stages. The fresh washing liquid is added to the last washing stage, in which the filter cake is already prewashed. The wash filtrate from each stage is collec...
Science projects are a great way for students to demonstrate their understanding of scientific concepts while following thescientific method. Here’s how you can turn this water filtration activity into ascience fair project! Create a Hypothesis: For example, “If a filter uses both cotton balls ...
The third method for mitigating the risk associated with process pauses is to explicitly quantify their impact during viral clearance studies. These studies will help determine what level of viral clearance can be claimed by the virus filtration step. They may also help inform which process ...
Researchers from the University of Massachusetts School of Medicine have developed a powerful and scalable method for isolating and purifying exosomes from mesenchymal stem cells, which is GMP-compatible. In their study, they compared the physical and chemical characteristics of exosomes produced by diffe...
A filter assembly and method of filtering a fluid containing particulates is provided having a filter element mounted on a horizontal mandrel, whereby the filter element and mandrel
9. A method according to claim 1 including the step of controlling the quantity of the filter medium which is transported to the wash path by quantity sensing or pressure sensing of the suspension prior to the supply thereof to the filter bed zone. ...