Cavity filling mutations at the thyroxine-binding site...
Also Trp fluorescence was used as a probe of denaturation. percentage of tetramer over total TTR was higher for TTR A108V (79.3 ± 9.2% tetramer) variant and for TTR A108I (93.7 ± 1.2%) than for TTR WT (71.7 ± 6.3%) and TTR V30M (30.6 ±...