Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e
Although IL-17A is involved in the recruitment and activation of neutrophils that prevent microbial spread in response to other bacteria and fungi,34,35 and IL-22 is known to act on intestinal epithelial cells to elaborate antimicrobial peptide expression,36,37 our data link these two processes ...
Filamentous fungi are capable of expressing native and heterologous proteins to high levels, making them well-suited for the large-scale production of enzymes and other proteins for industrial, pharmaceutical, animal health and food and beverage applications. Filamentous fungi are typically grown in myce...