Terminally differentiated keratinocytes do not possess a plasma membrane, instead they have evolved a thickened, highly insoluble structure, referred to as the cell envelope. This cell envelope owes its structural integrity and insolubi-lity to the presence of E-lysine-y-glutamyl cross-links (Sugawar...
摘要: SA1: To determine whether DNA-M at birth predicts future pulmonary function in the F1 generation we will 1) measure methylation of CpG sites genome-wide using DNA obtained within the first seven da…" [more]会议名称: 31st Congress of the European-Academy-of-Allergy-and-Clinical-...
18 AKT1 activity in the epidermis is increased by treatment with the mechanistic target of rapamycin complex 1/2 (mTORC1; regulatory associated protein of the MTOR complex 1 [RAPTOR]) inhibitor rapamycin,18 suggesting a role of RAPTOR in modulating AKT1 activity. Therefore we hypothesized that ...
Keywords: royal jelly extract; 10-hydroxy-2-decenoic acid; moisturizing; filaggrin; aquaporin; stratum corneum 1. Introduction Dry skin is caused by some factors including insufficient in the emollient oil of the skin surface, the decrease in the natural moisturizing factor (NMF) of the stratum ...