骨纤维异常增殖症(fibrous dysplasia, FD)又称为骨纤维结构不良,是一种良性骨组织疾病,由异常的纤维- 骨结缔组织取代正常的骨组织所导致,1938 年 Lichtenstein 提出此类疾病并予以命名,好发11-30岁,四肢躯干骨以股骨、胫骨、肋骨和肱骨发病多见。颅面骨以下颌...
骨皮质变薄,髓腔扩大,呈磨砂玻璃样改变,可伴有囊状阴影和斑片状骨硬化影,无骨膜反应。 2.MRI特点 病灶边界清楚,T1加权相呈均匀的略低信号,T2加权相呈高信号或混杂信号。 三、病理改变 1.大体 病灶位于髓腔内,为灰白色质韧、脆组织,橡皮样硬度,切面有砂砾感。有时可见胶冻样粘液变或囊性变。 2.镜下 正常...
CT显示病变骨质内部,不含软组织成分,可见骨质自溶,病变边缘硬化破坏,皮质破坏并可伴有周围软组织肿胀。MRI显示T1中等强度信号,T2高信号。 在组织学上,本病病变组织周围没有活跃生长的成骨细胞环绕,并且为细胞角蛋白阴性(cytokeratin-negative)(如图4)。 细胞遗传学显示,本病与3号及5号染色体异常有关。 非骨化性纤...
在具有多发性纤维性发育不良的患者的图像上,在股骨近端和中间 - 骨干中具有透明损伤,并且在腓骨中具有磨砂密度和钙化的损伤。 其他影像学研究: 您的医生可能会订购磁共振成像(MRI)或计算机断层扫描(CT)扫描以进一步评估病变。 MRI将更清楚地显示...
Eleven patients with proven fibrous dysplasia of the skeleton (FD) were examined using magnetic resonance imaging (MRI). Almost constantly T-weighted hypointense, T-weighted hyperintense (cystic) as well as T- and T-weighted hypointense (fibrous) areas within the lesion could be demonstrated, ...
Fibrous dysplasia, rare congenital developmental disorder beginning in childhood and characterized by replacement of solid calcified bone with fibrous tissue, often only on one side of the body and primarily in the long bones and pelvis. The disease appe
The initialtestrecommended in a suspected case fibrous dysplasia is X-ray which shows characteristic mottling and sclerotic changes with a “ground-glass” appearance. Computed Tomography clearly shows cystic and sclerotic lesions with smooth cortical margins and no soft tissue involvement. MRI shows low...
Fibrous dysplasia of bone affecting multiple bones.───骨质纤维的发育异常影响到多处骨头。 Objective To study MRI findings offibrous dysplasiainvolvement of cranial bones.───目的研究颅骨骨纤维异样增殖症的MRI表现。 Diagnosis: Fibrous dysplasia of the skull.───诊断: 颅骨纤维异常增殖. ...
fibrous dysplasia, café au lait skin pigmentation, and endocrine hyperfunction has been known as the classic form of the McCune–Albright syndrome. The Mazabraud syndrome refers to the combination of fibrous dysplasia and soft tissuemyxomas. Elevated cAMP is also implicated in the increasedcellular ...
CT and MRI To date,the diagnostic characteristics of osteofibrous dysplasia on computed tomography (CT) or magnetic resonance imaging (MRI) have not been well established.[54]However, Jung et al reviewed MRI scans of 24 pathologically proven cases and concluded that osteofibrous dysplasia showed a...