Furthermore, abnormalities in the ovaries are closely associated with the development of various gynecological diseases in women, such as polycystic ovary syndrome (PCOS), premature ovarian failure (POF), endometriosis, and other ovarian dysfunction and aging caused by abnormal ovarian fibrosis. These ...
In parallel, women are now also routinely genetically screened to determine whether they are carriers of recessive mutations that could put their offspring at risk for an inherited disorder. CF is an example of a disease with well-known deleterious effects on reproductive function in both sexes ...
Two women with CF and Turner syndrome have been reported in the literature. Both women were diagnosed with CF in infancy and Turner syndrome in their teenage years as part of an evaluation for short stature [34]. Klinefelter syndrome (karyotype 47,XXY or XY/XXY mosaicism) occurs in ...
Endometriosis is one of the most common causes of chronic pelvic pain and infertility that affects 10% of women of reproductive age. It is currently defined as the presence of endometrial epithelial and stromal cells at ectopic sites; however, advances in endometriosis research have some authors be...