APRI(Aspartate aminotransferase to platelet ratio index)评分系统是2003年由美国提出的评估肝纤维化和肝硬化的无创方法,计算公式为:APRI=(AST/ULN)×100/PLT(PLT单位109/L),成人APRI指数>2分,提示已经肝硬化。 而FIB-4(Fibrosis index based on t...
The FIB-4 Index can assist you in determining which patients need: Additional assessment of liver disease Referral to a specialist The easy-to-order, noninvasive Liver Fibrosis, Fibrosis-4 (FIB-4) Index from Quest Diagnostics yields a single score by combining: ...
而FIB-4(Fibrosis index based on the 4 factors)评分系统是2006年由Sterling提出,计算公式为:FIB-4=(年龄×AST)÷(血小板×ALT的平方根)。不同肝病FIB-4指数评价的阈值不同,慢性乙肝或丙肝,指数<1.45者,提示无纤维化或2级以下肝纤维化;>3.25者提示肝纤维化3～4级或以上;非酒精性脂肪肝,指数<1.3提示纤维化...
FIB-4 Index as a Non-Invasive and Inexpensive Predictor of Hepatic Fibrosis in a Primarily Uninsured African-American Population with Chronic Hepatitis C: 379Maheshwari, RahulYang, JianhuaMiller, LesleyOfficial journal of the American College of Gastroenterology | ACG...
FIB-4 index may represent a useful predictor of a subsequent decrease in insulin secretion, at least in a non-diabetic Japanese population.doi:10.1038/S41598-020-72894-8Tomoyuki FujitaMakoto DaimonSatoru MizushiriYuki NishiyaHiroshi Murakami
The ALBI score, FIB-4 index, and APRI were determined via the following formulas: (I) ALBI score = (log10 bilirubin (µmol/L) × 0.66) + (albumin (g/L) × − 0.0852), (II) FIB-4 index = (age (years) x AST (U/L)) / (PLT (109/L]) x (ALT ...
This study aimed at evaluating the predictive value of neutrophil-to-lymphocyte-ratio (NLR) and fibrosis-4 index (FIB-4), indices of inflammation and fibrosis, respectively, on CAD mortality. Data from 1460 CAD patients (1151 males, age: 68 ± 10 years, mean ± SD) were retrospectively ...
FIB-4 index for assessing the prognosis of hepatocellular carcinoma in patients with Child-Pugh class A liver function PURPOSE: We evaluated the prognosis of hepatocellular carcinoma (HCC) patients with Child-Pugh (C-P) class A based on FIB-4 index, which is a liver fibrosi... T Ito,T ...
Only 6 of 308 patients with a FIB4 index below the proposed low cut-off point (< 1.45) were under-staged, giving a high negative predictive value of 98%. Twenty-eight of 59 patients with a FIB4 index above the high cut-off point (> 3.25) were over-staged, giving a low positive ...
The prognostic value of the FIB-4 index in sepsis patients remains an area of active investigation. The preliminary evidence indicates that elevated FIB-4 levels may be associated with worse outcomes in sepsis, including increased mortality, longer ICU stays, and higher rates of organ dysfunction....