吉满生物H_FGF21 Reporter HEK-293 Cell Line是一种Luciferase报告基因细胞系。当FGF21结合FGFR1和β-Klotho(KLB)受体后,激活下游信号通路,从而激活荧光素酶(Luciferase)的表达。Luciferase读值即代表信号通路的激活效果,因此可用于FGF21相关药物的体外效果评价。
The present invention further relates to a method for detecting and optionally quantifying neutralizing antibodies against FGF21 present in a test sample using the reporter cell line of the present invention.トービー,マイケルハン,リューラルマン,クリストフ...
FGF21细胞系产品列表 部分结果: GM-C19834 :H_FGF21 Reporter HEK-293 Cell Line 使用Human FGF-21药物激活验证结果 吉满生物助力药物研发,紧随前沿靶点资讯,储备几百株现货细胞,覆盖GPCR、细胞因子、免疫检查点、TAA等多领域近200余个靶点。 来源:DDXCELL官方...
部分结果数据展示 GM-C25537：H_GLP1R Reporter HEK-293 Cell Line GM-C35007：H_GLP1R HEK-293 Cell Line GM-C33299：H_GLP1R CHO-K1 Cell Line GM-C24030：H_GIPR Reporter HEK-293 Cell Line GM-C35006：H_GIPR HEK-293 Cell Line GM-C35005：H_GIPR CHO-K1 Cell Line 使用Anti-H_GIPR hIgG...
GM-C19834 :H_FGF21 Reporter HEK-293 Cell Line 使用Human FGF-21药物激活验证结果 吉满生物助力药物研发,紧随前沿靶点资讯,储备几百株现货细胞,覆盖GPCR、细胞因子、免疫检查点、TAA等多领域近200余个靶点。 来源:DDXCELL官方 参考: 1.Doi: 10.1111/j.1476-5381.2011.01687.x. 2.Doi: 10.1021/acschembio....
GM-C19834 :H_FGF21 Reporter HEK-293 Cell Line 使用Human FGF-21药物激活验证结果 吉满生物助力药物研发,紧随前沿靶点资讯,储备几百株现货细胞,覆盖GPCR、细胞因子、免疫检查点、TAA等多领域近200余个靶点。 2020年底成立专业细胞系子品牌DDXCELL,同时已建...
To precisely observe the movement of WT cells, we established a WT cell line stably expressing a red fluorescent reporter in the cell nucleus and treated the cells with conditioned medium derived from scribKD cell cultures. Strikingly, after treating with conditioned medium of scribKD cells ...
It was expected that the fluorescence reporter would be used to isolate or detect Fgf21-positive cells using fluorescence-activated cell sorting. Unfortunately, we failed to isolate Fgf21-positive cells in the pancreas due to the low fluorescence intensity, although fluorescence was detected in the ...
TheiLite® FGF21 Assay Ready Cells are a genetically engineered reporter gene cell line responsive to FGF21 by specific and proportional expression of Firefly Luciferase. The receptor chain FGFR1c is overexpressed on the surface together with the co-factor β-Klotho which has been genetically opti...
This rAAV genome may further comprise a marker or reporter gene, such as a gene for example encoding an antibiotic resistance gene, a fluorescent protein (e.g. gfp) or a gene encoding a chemically, enzymatically or otherwise detectable and/or selectable product (e.g. lacZ, aph, etc.) ...