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The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling system regulates a variety of biological processes, including embryogenesis, angiogenesis, wound repair, tissue homeostasis, and cancer. It exerts these regulatory functions by controlling proliferation, differentiation, migratio...
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The molecular mechanism that initiates the formation of the vertebrate central nervous system has long been debated. Studies in Xenopus and mouse demonstrate that inhibition of BMP signaling is sufficient to induce neural tissue in explants or ES cells r
6. Mika, D., and Conti, M. (2016). PDE4D phosphorylation: A coincidence detector integrating multiple signaling pathways.Cell. Signal.28, 719–724. 转载须知 【原创文章】BioArt原创文章,欢迎个人转发分享,未经允许禁止转载,所刊登的所有作品的著作权均为BioArt所拥有。BioArt保留所有法定权利,违者必究。
FGF10 plays an important role in the morphogenesis of several tissues by control of mesenchymal-to-epithelial signaling. In the pancreas, mesenchymal FGF10 is required to maintain the Pdx1-expressing epithelial progenitor cell population, and in the absence of FGF10 signaling, these cells fail to...
FGF signaling antagonizes cytokine-mediated repression of Sox9 in SW1353 chondrosarcoma cells 来自 国家科技图书文献中心 喜欢 0 阅读量: 74 作者:JF Schaefer,ML Millham,BD Crombrugghe,L Buckbinder 摘要: Objective: The Sox9 transcription factor has emerged as an important determinant of chondrocyte ...