FGF basic modulates such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, neuronal function and neural degeneration. Transgenic overexpression of FGF basic results in excessive proliferation and angiogenesis is reminiscent of a variety of pathological...
Acidic FGFs and basic FGFs are the two prototypical members of the FGF family, which have a high affinity for heparin and are found to be associated with ECM (Extracellular Matrix Components). In contrast to VEGF (Vascular Endothelial Growth Factor), which is an en...
Sulfated malto-oligosaccharides bind to basic FGF, inhibit endothelial cell proliferation, and disrupt endothe- lial tube formation. J Cell Physiol 1996;168:657±67.Foxall C, Wei Z, Schaefer ME, Casabonne M, Fugedi P, Peto C, Castellot JJ Jr, Brandley BK: Sulfated malto-oligosaccharides ...
产品名称: FGF BASIC, PEPTIDE-1MG .0 订购此产品 供应商: Millipore 规格: EA 目录价: 库存状态: 三周到货 CAS编号: 应用范围: 生化实验 种属来源: 相关信息: Fibroblast Growth Factor basic peptide, Synthetic, brain derived (1-24) Description: Fibroblast Growth Factor basic peptide, Synthetic...
别名 Basic fibroblast growth factor; FGF basic; FGF-basic; BFGF; FGF-2; FGF B; FGF2; FGF2 basic; FGFB; Fibroblast growth factor 2 (basic); HBGF 2; HBGF-2; HBGF2; HBGH 2; HBGH2; Heparin binding growth factor 2 precursor; Prostatropin; FGF2_HUMAN. 研究领域 肿瘤 心血管 细胞生...
but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively sp...
These observed in vitro functions suggest FGF basic may play a role in vivo in the modulation of such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, and neuronal function and neural degeneration. Additionally, FGF basic may also p...
产品名称 Recombinant Human FGF basic/FGF2/bFGF(155aa) Protein 别名 重组人碱性成纤维细胞生长因子蛋白(basic/FGF2/bFGF),无动物源 | 重组人碱性成纤维细胞生长因子蛋白(basic/FGF2/bFGF)无动物源 | 重组人类 FGF basic/FGF2/bFGF(155aa) 蛋白 英文别名 Basic fibroblast growth factor Basic fibroblast ...
Human embryonic stem cell (hESC) cultures require FGF basic (also known as FGF-2 or bFGF) in cell culture media to remain in an undifferentiated and pluripotent state. Thermostable FGF basic was engineered for enhanced stability in culture media, without modification of its biological function. ...
The ATG initiation codon is always located in exon 1 or at the beginning of the first 5’ subexon, however, FGF2 (basic FGF, bFGF) and FGF3 (int-2), have additional alternative 5’ translated regions that initiate from upstream CUG codons (Plate 31.1A). These members, as well as ...