The mechanism of action of feverfew is not clear but may involve inhibition of prostaglandins, effects on platelet activity, inhibition of vascular smooth muscle contraction, or blockade of histamine release from mast cells. Current evidence suggests that the active agent in feverfew is parthenolide, ...
Mechanism of action Parthenolide inhibits serotonin release, an action that is thought to be a likely source of its effectiveness in migraine. Extracts have also been shown to reduce the production of prostaglandins (another possible mechanism) and leukotrienes. Interestingly, melatonin has been identifi...
Feverfew UpdateReports on the anti-inflammatory properties of the garden plant, feverfew or Tanacetum parthenium. Role in treating migraines and fever; Mechanism of action of parthenolide, an active chemical of feverfew.Vegetarian Times
Feverfew Update.Reports on the anti-inflammatory properties of the garden plant, feverfew or Tanacetum parthenium. Role in treating migraines and fever; Mechanism of action of parthenolide, an active chemical of feverfew.EBSCO_AspVegetarian Times...
While the mechanism of action of magnesium in migraine is not clearly understood, the metal ion is known to have strong vasodilating effects which may interrupt a vasoconstrictive phase of the migraine process; magnesium also inhibits platelet aggregation in a dose-dependent manner.Herbalgram...
An obesity-induced inflammatory response was induced in various co-culture systems using adipocytes (3T3-L1) and macrophages (RAW264.7) in vitro and the effect of PL and its mechanism of action were determined. PL effectively suppressed the adiposity-induced inflammatory responses by down-regulating ...