(analogous to specificity) determined by the fraction of positive cells that belong to the group; recall (analogous to sensitivity), as the fraction of group cells that were positive; and the F-score, calculated as the harmonic mean between recall and precision (F1 = 2 × (recall ×...
Fetal fraction (FF) is the percent of cell-free DNA (cfDNA) in the mother’s peripheral blood that is of fetal origin, which plays a pivotal role in noninvasive prenatal screening (NIPS). We present a method that can reliably estimate FFs by examining autosome single-nucleotide polymorphisms...
9 cm, AFI: 27.5 cm) with a normal fluid-filled abdomen and mild dilatation of both lateral ventricles (11 mm). The fetal intracranial assessment showed an enlarged cisterna magna (12 mm) and
little is known about mitochondrial involvement during prenatal life in humans. Human embryo implantation and fetal development are energy-intensive processes requiring substantial amounts of ATP. Consequently, mitochondrial dysfunction during these phases can compromise normal fetal development...
The ribosomal RNA depleted RNA fraction is termed the RiboMinus RNA fraction and is enriched in polyadenylated (polyA) mRNA, non-polyadenylated RNA, pre-processed RNA, tRNA, and may also contain regulatory RNA molecules such as microRNA (miRNA) and short interfering RNA (siRNA), snRNA, and...
The mean left ventricular ejection fraction (EF) was 29%. Approximately half of all patients had an EF <30%, and 14% had an EF between 40% and 45%. The most frequently reported medical history conditions other than heart failure included hypertension (79%), coronary artery disease (58%)...
FBS is the liquid fraction that remains after blood is drawn from bovine fetus coagulates. Serum is obtained by immediately centrifuging blood to remove cells, coagulation fibrinogens, and proteins. It is the most widely used serum supplement for in vitro eukaryotic cell culture (Puri et al.,...
Speckle tracking-derived left atrial stiffness predicts clinical outcome in heart failure patients with reduced to mid-range ejection fraction. J Clin Med 2020;9:1244. https://doi.org/10.3390/jcm9051244.Search in Google Scholar PubMed PubMed Central 28. Thomas, L, Muraru, D, Popescu, BA, ...
Normal growth characterised as trajectories within the interquartile range (25th–75th) on the GROW chart had a protective effect for EmCS (RR 0.64, CI 0.57–0.72) and Comp (0.67, 0.53–0.86), and no significant association with perinatal death (1.06, 0.51–2.18). Pregnancies with growth traj...
To determine the optimal size range of iNIPS, we compared the samples of various fetal fractions and found that the trend of three peak areas (115–125, 125–135 and 135–145 bp) was proportional to the fetal fraction (Fig. 1). Accordingly, we selected three ranges of DNA fragment ...