It is the most sensitive feel-good zone of the body You can only see a small part of the clitoris—the majority of it is internal! For women and people with vaginas, orgasms most commonly come from the clitoris, located above the vaginal opening and urethra (1, 2). The clitoris is ...
Hormone-sensitive lipase (LIPE) was highly expressed, with no difference between body weight groups. The relative abundance of genes involved in estrogen synthesis in the breast in ADOL was comparable to that of adult women (Fig. 4b, c). ...
A cocktail of 47 isotopically-labeled internal standards was spiked into the samples for metabolite quantitation. Peak areas of endogenous metabolites were normalized to the areas of their corresponding isotopically labeled structural analogues for quantitation. RNA-sequencing and analysis Total RNAs of ...
Dual-color FISH analysis was performed using a biotinylated (Nick Translation Systems, GibcoBRL, Carlsbad, CA) BAC DNA probe for the Grik1/Ncam2/Kcjn6Mx1 genes and a digoxigenin-11-dUTP labeled (DIG-NICK Translation Mix, Roche Diagnostics GmbH, Mannheim, Germany) DNA probe for EGFP (Behbo...
in the confidence interval, and lack of properly labeled data [34,35]. Due to the complex data structures, AI-aided model training is an extremely expensive endeavor and requires a high computational load, while the medical imaging datasets are too limited when compared to those for general ...
Cell origins are labeled by distinct colors. e Heatmap visualization of the dynamic gene expression over the pseudotime. Cells were divided into four states based on the differentially expressed gene clusters. f Expression pattern of the signature gene clusters for each cell state along the ...
Biotin-labeled fragments were pulled down using MyOne Streptavidin T1 beads (Life Technologies, Waltham, MA, USA). Hi-C DNA was amplified using the KAPA HiFi Library Amplification Kit (KAPA Biosystems, Wilmington, MA, USA). DNA size selection was performed using AMPure XP beads (Beckman ...
labeled adipocytes corresponded to the locations of their intracellular lipid droplets (Supplementary Fig.2a). Intriguingly, the membrane-encapsulated small lipid droplets labeled with DID from the donor were precisely delivered into the holes (intrinsic lipid droplets) of the DIO-labeled recipient either...
Genes that are not normally expressed in ovaries but are ectopically expressed in setdb1 GLKD are labeled in red or in blue. Blue indicates genes which are normally expressed in testis Full size image To directly test whether Sxl plays a role in controlling H3K9me3 deposition, we profiled ...
voxel size = 1 × 1 × 1 mm3), and smoothing with a two-dimensional (2D) spatial Gaussian filter with full-width at half-maximum of 3 mm. The CBF values used for the analysis were calculated by pairwise subtraction of labeled and control images by the perfusion model...